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Showing 1 to 10 of 10 for “"Membrane enzyme"”.
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Studies on the Proteolytic Activation of the Membrane Enzyme, Pyruvate Oxidase
Pyruvate oxidase is a peripheral membrane flavoenzyme which has been purified to homogeneity from Escherichia coli. The enzyme is a tetramer of four apparently identical subunits with a molecular weight of 60,000 each. Amino acid analysis reveals that only 46% of the amino acid residues are …
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L-DOPA production in a liquid membrane enzyme reactor: process development and modeling
Opened per request of the author, 7/8/2026. See libanswers ticket https://libanswers.library.gatech.edu/admin/ticket?qid=18631263
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The ATP synthase from spinach chloroplasts (Spinacea oleracea) : improved isolation and purification of the enzyme and conformational changes observed with fluorescent labels
… from Chloroplasts, CF0F1, is an integral membrane enzyme, which catalyses the synthesis of ATP from ADP and Phosphate. The reaction is driven energetically by proton-transport across the enzyme. The activity of the enzyme is regulated through a transmembrane pH-difference and a redox …
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Physical Mechanisms of Ca-ATPase Regulation in the Heart
The Ca-ATPase is an integral membrane enzyme which translocates two calcium ions from the cytoplasm of the cell to the sarcoplasmic reticulum lumen utilizing ATP breakdown as its energy source, in order to promote muscle relaxation. The focus of this research is the cardiac isoform of the Ca-ATPase …
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!Development of small molecule therapeutics against anti-infectious and anti-cancer drug resistance via structure-based drug design
… translocase (MraY) is an important membrane enzyme involved in the early-stage biosynthesis of bacterial peptidoglycans. As the inhibition of MraY leads to bacterial cell lysis, such MraY inhibitors (e.g., muraymycin) hold great promise for antibiotic development. However, the …
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Biochemical and pharmacological studies on blood platelets and erythmocytes in affective illness
… differences were detected in either platelet membrane ATPase or adenyl cyclase specific activity in any of the groups of patients studied, when compared to values obtained in control subjects. However, unipolar depressed and bipolar manic patients were shown to have a reduced erythrocyte …
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EPR and solid-state NMR studies on the mechanism of cytochrome bo3 ubiquinol oxidase from escherichia coli
… of heme-copper oxidase superfamily. This trans-membrane enzyme complex catalyzes two-electron oxidation of ubiquinol and reduction of molecular oxygen to water. During the process, the protons from ubiquinol are released to the periplasmic side of the membrane, whereas the protons used in the …
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Tissue injury and remodeling in rat hippocampal dentate gyrus following sodium-potassium-ATPase inhibition.
Na+, K+-ATPase is a ubiquitous membrane enzyme that plays an important role in maintaining neuronal excitability, ionic homeostasis and cell survival. Although failure of the Na+, K+-ATPase pump has been implicated in the pathophysiology of a variety of neurological conditions, the timeline and …
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Enzymology of DHHC-mediated Protein S-Acylation
… stability, and activity. A family of integral membrane enzymes called DHHC proteins because of a conserved Asp-His-His-Cys motif, catalyze protein <italic>S</italic>-acylation within cells. DHHC proteins have been associated with human diseases including cancers, Huntington's disease, and …
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Solution structure and biochemistry of an intramembrane aspartyl protease (IAP)
Intramembrane proteases (IPs) play important roles in numerous biochemical processes in all kingdoms of life, including cell differentiation, development and metabolism. IPs are attractive targets for therapeutics development and have been implicated in the pathogenesis of human diseases, such as …