Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Membrane Rafts"”.
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The glucocorticoid receptor plays a central role in mammalian reproduction and signal integration in pituitary gonadotropes
… function. This study investigated if membrane rafts play a role in GR and GnRH receptor (GnRHR) crosstalk and explored the mechanism involved in the mouse pituitary gonadotrope LβT2 cell line by dexamethasone (Dex), GnRH and both together.
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The role of phospholipase D1 in trafficking and processing of amyloid precursor protein
… lipid is phosphatidic acid (PA), which mediates membrane trafficking and is produced by a variety of enzymes, including phospholipase D (PLD). We previously demonstrated that a PLD isoform, PLD2, is required for the synaptotoxic and memory-impairing actions of amyloid beta in an AD mouse model. …
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Regulation of SNARE function during sperm capacitation to promote the acrosome reaction
… (SNARE) complex formation and movement into membrane rafts in preparation for the acrosome reaction. Two t-SNAREs and a v-SNARE form a trans-SNARE complex, which is required for exocytosis. The core complex along with other regulatory proteins exerts an inward force by zippering from the …
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Kinetic analysis of Fcγ receptor and T cell receptor interacting with respective ligands
… of tyrosine and lipid phosphorylation, membrane rafts, and actin cytoskeleton. These results provide new insights to understanding T cell discrimination.
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Identification and Characterization of the Helicobacter Pylori Vacuolating Cytotoxin Receptor
… that exploits the important and abundant plasma membrane sphingolipid, sphingomyelin, as a cellular receptor. Cellular sphingomyelin levels correlated strongly to sensitivity to VacA. Modulation of sphingomyelin levels specifically at the plasma membrane altered VacA-mediated intoxication. …
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The Regulation of Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 2 (SHP-2) in Brain Microglia
… also shows that SHP-2 is regulated by lipid rafts in gangliosides-activated microglia. It was reported that, in cultured rat brain microglia, gangliosides induce rapid and transient activation of the JAK-STAT pathway. I hypothesized that raft-mediated SHP-2 activation is involved in transient …
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"Funcionalidad de los microdominios de membrana en la señalización durante la maduración meiótica de anfibios"
… del factor promotor de la maduración (MPF). Los rafts de membrana, en particular la estructura invaginada de las caveolae, podrían proporcionar un ambiente óptimo para la interacción entre la progesterona y el ovocito en la maduración meiótica. Sin embargo, las bases moleculares y los mecanismos …
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Solid-state NMR spectroscopy applied to model membranes: effects of polyunsaturated fatty acids
… are taken up into phospholipids in the plasma membrane. Thus the focus here is on the plasma membrane as a site of potential structural modification by DHA. Within cellular membranes, the huge variety of molecules (called lipids) which constitute the membrane suggest inhomogeneous mixing, thus …