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Showing 1 to 18 of 18 for “"Melting point depression"”.
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Melting point depression in biodegradable polyesters
… into the crystallisation kinetics and melting point depression of poly(L-lactideco-meso-lactide) with approximately 3.3% D-lactide content (PLA 3051D) was undertaken. The rate of crystallisation was too slow for a crystallisation exotherm to be detected by the DSC, therefore hot-stage …
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Structure-property relationships of novel cellulose esters
… the C₁₂ - C₁₄ waxy tri-esters revealed separate melting transitions (T<sub>m,L</sub> and T<sub>m, H</sub>) for ester substituents and main cellulose chains, providing evidence for the existence of a separate (crystalline) phase formed by the ester substituents. Main-chain T<sub>mS</sub> of waxy …
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Study of the miscibility, morphology, crystallization, and melting behavior of blends of poly(3-hydroxybutyrate) and poly(vinylidene fluoride)
… behavior in the liquid state. Studies of the melting of isothermally crystallized samples indicate a melting point depression for melt blended PVDF/PHB but no equilibrium melting point depression for the solution blends. Growth rate studies on the α phase of PVDF reveal that its radial growth …
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Thermal Properties of Indium Nanoparticles and Gold Silicide Formation by Scanning Nanocalorimetry
… films. The unique finding is to determine the melting temperature of metastable phase using calorimetry, which is ∼60°C below the eutectic melting point (363°C). The heat of fusion (26.4 kJ/mol) of the metastable phase has also been obtained. The metastable phase is analyzed to be …
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Studies into solid core drug delivery system using haemoglobin as a model drug and supercritical fluid processing for encapsulation
… carbon dioxide (CO2) as a processing media. The melting behaviour of saturated fatty acids (lauric, myristic, palmitic and stearic acid) and pluronics (F-38, F-68, F-77, F-127 and F-108) were studied under pressurised CO2 to identify the coating parameters. These excipients showed a melting point …
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Exploring co-milling as a strategy to improve the dissolution of poorly water-soluble drugs
… testing. A strong linear correlation between melting point depression and maximum drug concentration (cmax) in vitro (R2 > 0.98) highlighted melting point depression as a promising critical quality attribute to anticipate drug supersaturation and for stability purposes. Fenofibrate, in …
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Heat Transfer Enhancement of Phase Change Materials for Thermal Energy Storage Systems
… selected types of PCMs are paraffin waxes with melting point temperatures of 28-72◦C. In an effort to study both convective and conductive heat transfer enhancement the experimental analysis has been divided into two phases. In the first analysis, silicone oil is selected as a heat transfer …
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Investigating Crystallization Tendency, Miscibility and Molecular interactions of drug-polymer systems for the development of amorphous solid dispersions
… transition temperature (Tg), crystallinity and melting point depression along with theoretical calculations such as solubility parameter were performed to study drug polymer miscibility. Molecular interactions were predicted by using Tg deviations and molecular modeling. Physical states of drug …
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Investigation of injection moulding for novel drug delivery systems. An investigation into the use of injection moulding to produce pharmaceutical dosage forms and to understand the relationship between materials, processing conditions and performance, in particular drug release and stability
… phase diagram constructed based on the melting point depression and the Flory-Huggins lattice solution theory provided the explanation for the phase separation and crystallisation behaviour of ibuprofen-HPMCAS systems. The advanced characterisation techniques like DMA, 2D XRD and 3D …
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Size effects on self-assembly and melting of silver-alkanethiolate on inert surfaces
… provide an excellent platform to study the melting characteristics of crystalline lamellae of polymeric materials with the thickness in the nanometer scale. This system is also unique in that each crystal has integer number of layers – magic-number size (thickness). The size of the crystals …
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Solubility Enhancement and Precipitation Inhibition of Poorly Water Soluble Compounds Utilizing Hot Melt Extrusion Technology
… (KTZ) using hot-melt extrusion technology. The melting point depression approach was utilized to determine the miscibility and solubility of the model compounds within Soluplus® , of which felodipine demonstrated higher solubility when compared to ketoconazole (14% vs 4.3% w/w) at room …
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Investigations of Structure–Property Relationships in Semicrystalline Thermoplastic Polymers: Blown Polyethylene Films and Polyacrylonitrile Copolymers
… The MA decreased both the glass transition and melting temperatures. Melting point depression was sufficient in the two highest MA content copolymers to allow for complete melting prior to the onset of thermal degradation using modest heating rates (20 ºC/min). Insight into the heterogeneous …
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Chemical and Physical Modifications of Semicrystalline Gels to Achieve Controlled Heterogeneity
… exhibited enhanced crystallizability, decreased melting point depression, and faster crystallization kinetics. Phase separation between the hydrophilic sulfonated blocks and hydrophobic PEEK blocks, aided by polymer crystallization, resulted in enhanced water uptake, superior proton conductivity, …
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Functional ionic liquids for use in pharmaceutical applications
… will interact. However, common trends regarding melting point depression, thermal stability, and solubility were determined. The most exciting results were exhibited during the biological testing, as several of the synthesized ILs demonstrated improved biological activity over the precursor ions. …
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Protein adsorption on nanostructured silica surfaces
… 𝛽-lactoglobulin on both sides of the isoelectric point of the protein. Resulting data were evaluated with the Guggenheim – Anderson – de Boer adsorption isotherm equation which accounts for multilayer adsorption from liquid phases. The orientation of the globular protein cytochrome c adsorbed on …
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Size dependence and odd/even effect in the melting of 2D lamellar crystals
Made available in DSpace on 2013-08-22T16:42:11Z (GMT). No. of bitstreams: 2 Lito_de la Rama.pdf: 8587134 bytes, checksum: 3348b80b4e5c0b0fcae5c001fcf7a311 (MD5) license.txt: 4065 bytes, checksum: fdeb9e289c81786abacb63b0b9cac6f4 (MD5)
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The interaction between silicate minerals and C-O-H bearing melts in the Earth's mantle
… examine the effect of volatile components on the melting of mantle rocks at conditions of the deep upper mantle (~180-400 km). Chemical compositions, including H2O contents, of hydrous melts, compatible with those that would form by small degree melting of an upper mantle peridotite at 180 km …
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Rational Design of Poly(phenylene sulfide) Aerogels Through Precision Processing
… - Hansen solubility parameters and fitting melting point depression data. The influence of polymer composition on PPS aerogel properties was then characterized. As polymer concentration increased, aerogel density and mechanical properties increases, and porosity decreased. The particular …