Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 59 for “"Medicine (human and vertebrates)"”.
-
Protein FOG at the interface between G streptococci and human host defence lines
… (GGS) may be of four different species and may infect humans and also animals. S. dysgalactiae equisimilis most commonly cause human GGS infections. These bacteria are part of the normal flora, but can cause pharyngitis, erysipelas and impetigo. In the immunocompromised host severe …
-
Pain induced by propofol - clinical studies on drug composition and adminstration
… market to allow for better patient satisfaction and faster recovery after anaesthesia and sedation. Propofol (2,6-di-isopropylphenol), one of our most common iv anaesthetics, is associated with pleasant sleep and rapid recovery with little postoperative nausea. When used for anaesthetic induction …
-
Assessment and treatment of dizzy patients in primary health care.
… this thesis aims to study the assessment and treatment of dizzy patients in primary health care. Interventions in papers I, III and IV comprised a vestibular rehabilitation programme. In paper I, patients with multisensory dizziness were randomized to intervention group or control group. …
-
Laminins in blood vessel development and disease -functional aspects in angiogenesis, atherosclerosis, and muscular dystrophy
… such as cell migration, proliferation, survival and differentiation. Vital components of all basement membranes are laminins, heterotrimeric combinations of different laminin chain isoforms. The different laminins and their subunits largely have a developmental and tissue specific distribution. …
-
Health Promotion Intervention in Mental Health Services
The aim of this thesis was to define and develop the concept of health promotion in mental health services as well as to develop a questionnaire to measure patients? subjective experiences of health promotion intervention in mental health services. The samples consisted of 12 patients in study I …
-
Mechanisms behind the lipid-lowering effects of ACTH - Studies in different experimental models
… Adrenocorticotrophic hormone (ACTH) has strong and direct lipid-lowering effects in man. All apoB-containing lipoproteins, i.e. VLDL, LDL, Lp(a), are reduced by 25-30%. In contrast, levels of HDL increase about 10%. In hepatic cell cultures, ACTH inhibits expression and secretion of apoB. In …
-
Hypoxia-induced phenotypic modulation of human neuroblastoma cells
… stages. Low differentiation stage and high tumour stage correlate to poor outcome. In earlier studies we have found that hypoxia induces dedifferentiation of neuroblastoma cells, which implies that hypoxia evokes a more aggressive phenotype. Here we employ microarray analysis to …
-
Signal transduction in macrophages. Intracellular pathways activated by microbial constituents
… in the defense against infection by phagocytosis and by production of inflammatory mediators. Such mediators are TNF? and eicosanoids. Many microbial agents elicit arachidonate release in macrophages that lead to the formation of eicosanoids. This thesis is based on studies performed with the use …
-
Infections in small children and their families - symptoms,consultations and antibioitcs
Infectious symptoms in infants and their families are common. With rising age the number of symptom day decreases, but increases again for the parents of infants. About one quarter of the symptom days lead to absence from daycare among the infants but the social remuneration system was used by the …
-
Childhood sexual abuse. Women's Mental and Social Health Before and After Group Therapy
… study was to evaluate changes in psychological and social variables before and after group therapy for adult women who were sexually abused in childhood. Other aims were to describe and evaluate the traumafocused group therapy by consumer satisfaction, to describe the women's health before group …
-
WOMEN WITH IRRITABLE BOWEL SYNDROME. Aspects of quality of life and health.
… number of people, predominantly women. Etiology and pathophysiology is insufficiently understood, but the research over the past decade has led to progress in the understanding of IBS, and it is generally accepted that the symptoms of IBS are multidetermined. However, management of IBS is still a …
-
IRON NUTRITION DURING EARLY CHILDHOOD. Factors influencing iron status and iron intake.
… describe the prevalence of iron deficiency (ID) and factors influencing iron status and iron intake among otherwise healthy children. The specific aim in paper I+II was to describe the prevalence of ID among 2 ½-year-old children in relation to intake of cow's milk and follow-on formula. The …
-
Mechanisms for Targeting of Proteins to Secretory Lysosomes of Haematopoietic Cells
… role by the production of antibiotic proteins and peptides. These are targeted for storage in secretory lysosomes and other neutrophil granules for subsequent release by regulated secretion in an inflammatory process. However, the granule content is very potent and may cause tissue damage when …
-
The impact of genetic, environmental and life-style factors on male reproductive function
… reproductive function have been observed. In Finland, the sperm concentration was found to be substantially higher than in Denmark. In parallel, the incidence of testicular cancer (TC) and of congenital malformations of male genital organs is significantly higher in Denmark as compared to Finland. …
-
Recombinant CXCR4/CCR5 hybrid receptors as tools for studies of HIV-1 receptor usage
The chemokine receptors CCR5 and CXCR4 are required, together with CD4, for the entry of HIV-1 into target cells. CCR5 using HIV-1 dominates during transmission and the asymptomatic phase of infection. During progression, virus phenotypes with the ability to use CXCR4 emerge in about 50% of …
-
The role of the leukemia-associated ETO homologue repressors in hematopoiesis
… this chimeric protein have impaired granulocytic and erythroid differentiation with accumulation of myeloblasts. The transcriptional co-repressor ETO (Eight Twenty One) was identified from the cloning of AML1-ETO. Subsequently, MTGR1 (Myeloid Translocation Gene-Related protein 1) and MTG16 …
-
THE ROLE OF PHOSPHODIESTERASE 3B IN CAMP-MEDIATED REGULATION OF INSULIN SECRETION
… by various combinations of ?-cell failure and insulin resistance leading to hyperglycemia and glucose intolerance. In order to maintain glucose tolerance in the insulin resistance state, increased insulin secretion is a requirement and it is because of inadequate islet adaptation that …
-
Progenitor cells in the postnatal central nervous system, characterization and genetic manipulation
… postnatal brain; the subventricular zone (SVZ) and hippocampus. The SVZ-derived cells specifically migrate to the olfactory bulb where they give rise to new interneurons. We have genetically manipulated the postnatal SVZ progenitor cells with the aim to direct them to a neuronal fate in the …
-
Molecular and morphological studies on non-healing venous leg ulcers.
Chronic skin ulcers are a major health problem and an increasing burden on health care providers. These ulcers have various underlying causes, such as venous or arterial insufficiency, diabetes, or vasculitis. Non-healing venous leg ulcers represent a condition characterized by excessive …
-
The G-protein coupled receptor CMKLR1/ChemR23: Studies on gene regulation, receptor ligand activation, and HIV/SIV co-receptor function
… role in this communication. Cells synthesize and release signalling molecules (ligands), which produce a specific response only in those cells that have a receptor for that ligand. The total number of GPCRs is estimated to be around 800 where approximately 160 still are "orphans", meaning that …
Page 1 of 3