Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Medicinal compounds"”.
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A correlation of physicochemical properties of selected medicinal compounds to their anatomical therapeutic chemical classification
… system would prove beneficial for further medicinal substances development. Nevertheless, such studies are seldom found in the literature, and thus although mapping of ATC codes would provide beneficial information, the process is a challenging one (Wang et al., 2013). The aim of the study …
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Methodology for the syntheses of pharmaceutically significant functional groups
… features emerge upon analysis. For example, many medicinal compounds contain combinations of nitrogen-containing heterocycles, polar functional groups such as fluorides or sulfoximines, and stereoisomers that are vital to their bioactivity. As a result, new methods to synthesize these important …
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Diastereoselective α-Alkylation of Chiral β-Borylated Esters
… methodologies and various biological and medicinal compounds has increased significantly over the last decade. This thesis reports the development of a novel diastereoselective reaction for the α-alkylation of chiral β-borylated esters. We propose that standard deprotonation of chiral …
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Dynamics and Catalytic Resolution of Selected Chiral Organolithiums
… as ways to access enantioenriched organolithium compounds for use in asymmetric synthesis. Since certain electrophiles consume the chiral ligand, it is desirable to render this process catalytic in the chiral ligand.</p> <p>As part of a larger study on the amenability of chiral organolithiums to …
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Mangrolide A, A Novel Marine Derived Polyketide with Selective Antibiotic Activity
… nature to produce complex, biologically active compounds has inspired researchers throughout history. The isolation of these molecules has been instrumental in the discovery of many medicinal compounds, especially to combat infections caused by pathogenic bacteria. Antibiotic resistance is a …
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Sustainable strategies for alcohol halogenation
Alkyl halides appear widely in the structures of medicinal compounds and as key synthetic precursors in the pharmaceutical industry. Bimolecular nucleophilic substitution reactions of alcohols are commonly employed in the formation of new carbon–halogen bonds. However, achieving substitution at the …
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Organic Synthesis: Taming Chemistry using Enabling Technologies
… flow chemistry to discovery and development of medicinal compound synthesis and new chemical methodologies respectively. It is divided into three distinct sections. The first section addresses a brief introduction to flow chemistry, highlighting the advantages and challenges that have been faced …
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Ethnobotany of Namaqualand : the Richtersveld
… plants for subsistence. Firewood is used daily, medicinal plants are collected regularly and edible plants as well as plants used for household and other activities (such as dyeing of leather) are often used. This project can be seen as a rescue operation to obtain information on the use of …