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Showing 1 to 12 of 12 for “"Medial septum"”.

  1. The Effect of Selective Cholinergic Lesion of Medial Septum on Recognition Memory

    Cai, Li2018

    … neurotoxin, 192IgG-saporin (SAP), into the medial septum (MS) of Sprague-Dawley rats was utilized to establish an animal model of cholinergic deficit of the septal-hippocampal tract, which had been expected as a pathologic model of memory impairment for Alzheimer's disease (AD). Three types …

    duquesne Repository record

  2. Morphological evidence for a substance P projection from a medial septum to hippocampus

    Shurlow, Carol L.East Carolina University2023

    ecu Repository record

  3. Selective Lesion of Cholinergic Neurons of the Septal-Hippocampal Tract: Memory and Learning

    Fitz, Nicholas2018

    … that the loss of cholinergic function in the medial septum (MS), observed early in many forms of dementia, contributes to memory losses characterized in these diseases. The studies of this dissertation examined whether the selective loss of cholinergic neurons in the MS impairs acquisition of …

    duquesne Repository record

  4. Hippocampal Output to the Septum Regulates Locomotion and Exploration

    Chen, Yuh-Tarng2024

    … Furthermore, we found that the DH-septum inhibitory pathway is critical for regulation of locomotion and exploratory behavior. Activation of the DH inhibitory output to the medial septum complex (MSc) decreased animals' distance traveled and increased immobility in the open field. …

    utswmed Repository record

  5. The Steroid Sulfatase Inhibitor (p-O-Sulfamoyl) - Tetradecanoyl Tyramine (DU-14) Enhances Memory Retention in Passive Avoidance in Rats with Hippocampal Cholinergic Deficit

    Abitoye, Phebian Arinola2017

    … the immunotoxin 192 IgG-saporin (SAP) into the medial septum, and tested using a step-through passive avoidance paradigm. There was a greater than 80% decrease in ChAT activity in the hippocampi of animals treated with SAP (p < 0.0001). There was also a 24.1% decrease in ChAT activity of in the …

    duquesne Repository record

  6. Age-Related Alterations in Orexin Modulation of Septo-Hippocampal Neurotransmission

    Stanley, Emily Marie

    … and memory, such as the hippocampus and the medial septum (MS) of the basal forebrain. Within the MS, orexin innervates cholinergic and GABAergic parvalbumin (PV) containing neurons that project to the hippocampus via the septo-hippocampal pathway. This anatomy suggests that orexin exerts …

    south-carolina Repository record

  7. Theta oscillations, timing and cholinergic modulation in the rodent hippocampal circuit

    Climer, Jason Robert2016

    The medial temporal lobe (MTL) is crucial for episodic and spatial memory, and shows rhythmicity in the local field potential and neuronal spiking. Gamma oscillations (>40Hz) are mediatepd by local circuitry and interact with slower theta oscillations (6-10 Hz). Both oscillation frequencies are …

    bu Repository record

  8. Low-Frequency-Induced Synaptic Potentiation: a Paradigm Shift in the Field of Memory-Related Plasticity Mechanisms?

    Habib, Diala2010

    … single pulse stimulation (1 Hz) of the medial septum (MS) and CA3 hippocampal (H) commissural fibres results in a long-lasting potentiation of field excitatory postsynaptic potentials (fEPSPs) in CA1 of urethane-anesthetised rats (MS-H-LTP). MS-H LTP is long lasting (>5 h), requires a …

    queens Repository record

  9. Disrupted female reproductive cyclicity and gonadotropin-releasing hormone neuron dysfunction in a mouse model of temporal lobe epilepsy

    Li, JiangUniversity of Illinois at Urbana-Champaign2020

    … In KA-injected males, only GnRH neurons in the medial septum displayed elevated firing. For both males and females, GnRH neuron intrinsic excitability was higher than in controls on both diestrus and estrus. On diestrus, the GnRH neuron firing rate was not correlated with the EEG seizure burden …

    uiuc Repository record

  10. Role of galanin in synaptic transmission and plasticity in the CA1 area of the rodent hippocampus

    Coumis, UraniaThe University of Edinburgh2005

    … acetylcholine by neurones projecting from the medial septum and nucleus ofMeynert to the hippocampus in rodents. Galanin inhibits acetylcholine and glutamate release, thereby depressing excess neuronal excitability in the brain. Although this effect established galanin as an endogenous …

    edinburgh Repository record

  11. Auswirkungen der Überexpression von neuronalem p21ras auf cholinerge Septumneurone der Maus : eine stereologische Studie

    Ziller, Matthias Georg

    … von p21ras auf cholinerge Neurone des Medialen Septums (MS) hat. In p21ras-transgenen Mäusen wird aktiviertes ras unter der Kontrolle unter der Kontrolle des neuronenspezifischen Synapsin I-Promotors exprimiert. In adulten p21ras-transgenen Mäusen konnte hier gezeigt werden, dass das …

    freiburg-diss Repository record

  12. Forebrain Acetylcholine in Action: Dynamic Activities and Modulation on Target Areas

    Zhang, Hao2009

    … recording, putative cholinergic neurons in medial setpal area (MS) were found with firing rate dynamics matching the phasic ACh release. </p><p> Second, to further elucidate the dynamic activities and physiological functions of cholinergic neurons, putative cholinergic MS neurons were …

    duke Repository record