Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Mechanosensitive Channels"”.
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Exploring the Dynamics of Mechanosensitive Channels Utilizing a Post Translational Modification Approach
… and changes in osmolarity. The bacterial mechanosensitive channel of large conductance (MscL) and the mechanosensitive channel of small conductance (MscS), from E. coli, have been the most studied mechanosensors to date. These channels coordinate a response to rapid changes in osmolarity …
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Sensory Transduction in Enteroendocrine Cells
… This thesis focuses on voltage gated ion channels and the transient receptor potential (TRP) superfamily in I cells and enterochromaffin cells using the model tumour cell lines STC-1 and KRJ-I respectively.<br/>Electrophysiology and PCR was performed on STC-1and KRJ-I model cell lines to …
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Molecular Dynamics Studies of the *Gating Mechanism of a Mechanosensitive Channel
Mechanosensitive channels are integral membrane proteins that gate in response to tension in the membrane. One such channel, MscL, poses an especially interesting challenge to modelers both because the channel is activated by membrane tension alone, and because the transition to the open state …
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The Role of the Stereociliary Glycocalyx in Hair Bundle Cohesion
… into the electrical language of neurons. The mechanosensitive organelle of the hair cell is the hair bundle, a cluster of linked, finger-like, membrane-ensheathed projections, stereocilia, emerging from the cell's apical surface. As a structure, the hair bundle is highly conserved, changing …
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Molecular Basis of Mechanosensitivity
… is thought to be the opening or closing of mechanosensitive channels, but the clonal nature of the first mechanotransducers is still largely unknown. The objective of my research was to identify molecules involved in mechanosensory transduction by both studying known channels as well as …
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Molecular Dynamics Studies Of The Gating Mechanism Of A Mechanosensitive Channel
Submitted by Meng Tao (mengtao2@illinois.edu) on 2012-10-12T23:59:36Z No. of bitstreams: 1 Gullingsrud.pdf: 9847446 bytes, checksum: d830d33e4dfe17fd16751f5656ebd512 (MD5)
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Droplet Interface Bilayers for Mechano-Electrical Transduction Featuring Bacterial MscL Channels
… the behavior of the Escherichia Coli mechanosensitive (MS) channel MscL, when incorporated within a droplet interface bilayer (DIB). The activity of MscL channels in an artificial DIB system is demonstrated for the first time in this document. The DIB represents a building block whose …