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Showing 1 to 13 of 13 for “"Mechanical heart valves"”.
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Complications of anticoagulation in pregnant women with mechanical heart valves
Includes abstract. Includes bibliographical references.
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Haemorrhage and Other Complications in Pregnant Women on Anticoagulation for Mechanical Heart Valves; a Prospective Observational Cohort Study
… in anticoagulated, pregnant patients with mechanical heart valves until 42 days postpartum. Methods: In a tertiary single-centre, prospective cohort, 178 consecutive patients at the cardiac-obstetric clinic were screened for warfarin use between 1 July 2010 and 31 December 2015. Of 33 …
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Application of passive flow control to mitigate the thromboembolic potential of bileaflet mechanical heart valves: an in-vitro study
Implantation of a bileaflet mechanical heart valve (BMHV) continues to be associated with risk of thromboembolic complications despite anti-coagulation therapy. Mechanical heart valves have been the gold standard in valve heart replacement since the 1950s with BMHVs currently still being the valve …
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3-DIMENSIONAL NUMERICAL AND EXPERIMENTAL STUDIES TO MODEL ARTIFICIAL HEART VALVES HEMODYNAMICS
The characterization of the artificial heart valves flow fields is a crucial step to evaluate the performances on improving heart valve engineering. With the advancement of Computational Fluid Dynamics, we are able to study the complex hemodynamics in details such as stagnation, recirculation zones …
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A Computational Model for Design Optimization of Bioprosthetic Heart Valves
<p>Heart valves play an important role in directing blood flow and preventing back flow in the heart. Design and development of bioprosthetic heart valves has been a major focus of research in the field of cardiovascular engineering as they are a better replacement for natural diseased valves than …
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Evaluating Treatment of Antiphospholipid Syndrome during Pregnancy with Knowledge Synthesis Methods
… to its exploration in pregnant women with mechanical heart valves. Although heterogeneity of PK analysis methods in the literature was striking, apparent clearance of these medications was consistently increased during pregnancy, likely based on the physiological changes in pregnancy. While …
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A Novel Multiblock Immersed Boundary Method Enabling High Order Large Eddy Simulation Of Pathological And Medical Device Hemodynamics
… device performance such as stent grafts and mechanical heart valves. Previous studies indicate the presence of highly disturbed, transitional and mildly turbulent flow in healthy and pathological arteries. Accurate simulation of the transitional flow requires high order numerics together with …
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Development of a Virtual Scientific Visualization Environment for the Analysis of Complex Flows
… system, particularly for flow through mechanical heart valves and inside the heart left ventricle (LV). The simulation provides three-dimensional (3-D) visualization of in-vitro heart flow mechanics, allowing global, volumetric flow analysis, and a useful environment for comparison with …
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Vortex Dynamics and Energetics in Left Ventricular Flows
Left ventricular flows in the human heart are very complex and in the presence of a diseased condition, such as unhealthy or prosthetic heart valves, the complexity of the flow is further increased. The intricacy of the heart geometry combined with the pulsatile character of the flow, the …
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Hybrid Electrospun Transcatheter Aortic Heart Valves for Tissue Engineering Applications
Bioprosthetic and mechanical heart valves are suboptimal due to both calcific degeneration and the need for lifelong anticoagulation treatment. Tissue engineering (TE) has the potential to overcome these and other shortcomings by providing viable valves capable of growth, remodelling, and repair. …
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Hemodynamic Flow Characterization of St. Jude Medical Bileaflet Mechanical and Bioprosthetic Heart Valve Prostheses in a Left Ventricular Model via Digital Particle Image Velocimetry
The performance of the heart after a valve replacement operation will greatly depend on the flow character downstream the mitral valve thus a better understanding of the flow character is essential. Most in vitro studies of the flow downstream of a MHV have been conducted with the valve in the …
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A Comparative In Vitro Study of the Flow Characteristics Distal to Mechanical and Natural Mitral Valves
Mechanical heart valve (MHV) flows are characterized by high shear stress, regions of recirculation, and high levels of turbulent fluctuations. It is well known that these flow conditions are hostile to blood constituents, which could lead to thromboembolism. In the ongoing effort to reduce …