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Showing 1 to 1 of 1 for “"Mechanical chemistry"”.
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Gates and Latches: the mechanochemistry of ATP binding in kinesin 1 and Eg5
This thesis explores the role of mechanochemistry in two biological systems. The first system investigated involves cargo transport along microtubule filaments by Kinesin 1. A gating mechanism is needed to coordinate ATP binding to the two catalytic domains within Kinesin 1 in order to prevent …