Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 177 for “"Mechanical Loading"”.
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Mechanical loading and cartilage physiology
Whilst mechanical impact is known to be essential for cartilage maintenance, it has been noted that altered joint loading and increased force may lead to cartilage degradation and increase the risk for the development of osteoarthritis (OA). This study investigated the cellular responses of …
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Skeletal adaptation to reduced mechanical loading
… its mass and architecture in response to its mechanical environment. Yet control of this process by mechanical cues is poorly understood, particularly for unloading. Defining the fundamental mechanoregulation of bone adaptation is critical for the better understanding and mitigation of bone …
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Skeletal adaptation to reduced mechanical loading
… its mass and architecture in response to its mechanical environment. Yet control of this process by mechanical cues is poorly understood, particularly for unloading. Defining the fundamental mechano-regulation of bone adaptation is critical for the better understanding and mitigation of bone …
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Combined mechanical loading of composite tubes
… tubes subjected to combined axial and torsional loading. An elasticity based analytical model was developed to predict stresses and deformations in composite tubes subjected to combined thermomechanical loading. Material nonlinearities were modeled using the Endochronic Theory. The effect of …
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Suppression of intention tremor by mechanical loading
… Institute of Technology, Dept. of Mechanical Engineering, 1979.
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The role of mechanical loading in chondrocyte signaling pathways
… degradation. Accumulating evidence suggests that mechanical loading contributes to the regulation of cartilage homeostasis. However, the underlying mechanisms are not clear as to how varying magnitudes of mechanical loading trigger differential intracellular signaling pathways at sub-cellular …
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The effect of mechanical loading on bone during growth
… has been experimentally investigated by inducing mechanically driven microdamage. Exercise can affect both modeling and remodeling of bone and has a significant influence on bone mineralization. However, few longitudinal studies have been performed during growth to determine if bone modeling …
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Microcracking in composite laminates under thermal and mechanical loading
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 1995.
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Peripheral mechanical loading and the mechanism of abnormal intention tremor
… Institute of Technology, Dept. of Mechanical Engineering, 1981.
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Fracture and failure of layered materials under thermo-mechanical loading
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 1997.
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Mechanical Loading for Modifying Tissue Water Content and Optical Properties
… such as water and protein, and the mechanical and optical properties of human skin is important to understand its complex nature. Localized mechanical loading has been proven to alter optical properties of tissue, but the mechanisms by which it is accomplished have not been studied …
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Mechanical loading impacts intramuscular drug transport : impact on local drug delivery
… schema to investigate the impact of controlled mechanical loads applied to skeletal and cardiac muscle tissue on intramuscular transport of locally delivered drug. In a series of studies, we examined how the interaction between architectural configuration and functional mechanics alters the …
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Finite Element Analysis to Investigate Lipid Absorption in UHMWPE Under Mechanical Loading
… in total knee arthroplasty (TKA) due to its mechanical strength, low friction, and biocompatibility. Despite advancements in crosslinking and post-irradiation stabilization, oxidative degradation remains a limitation, contributing to long-term implant failure. Recent studies have shown that …
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Experimental assessment of cracked steel beams under mechanical loading and elevated temperatures
… of fatigue cracks that are the result of cyclic loading from daily traffic. With no available data on failure behavior of cracked steel beams under fire, this thesis introduces a new testing protocol for evaluating the response of cracked steel beams under elevated temperature. Specifically, the …
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α7β1 integrin regulation of skeletal muscle growth in response to mechanical loading
… of skeletal muscle mass in response to mechanical loading. The purpose of this study was to 1) to utilize an automated computer program (SMASH) to reassess myofiber cross-sectional area in previously collected samples, and 2) to determine the mechanism by which the α7β1 integrin can …
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Vascular and Mechanical Changes in Bone in Response to Chronic Ischemia and Mechanical Loading
… paper will examine the effects of ischemia and mechanical stimulation on bone remodeling. An immunohistochemistry protocol for vessel marking in bone was also developed. Ischemia was induced in a mouse model to determine vascular and mechanical property changes in bone in response to hypoxia, …
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Cross-sectional Morphology and Mechanical Loading in Plio-Pleistocene Hominins: Implications for Locomotion and Taxonomy
… by examining cross-sectional properties and mechanical loading patterns in the proximal and midshaft femur of Paranthropus, fossil Homo sp. and H. erectus. Modern human and Pan models are used for comparative purposes. Cross-sectional properties in the proximal and midshaft femur of fossil …
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Estrogen Regulation of the Wnt/β-catenin Pathway in Osteocytes in Response to Mechanical Loading
… to be the primary cell involved in sensing mechanical loads. The Wnt/β-catenin pathway is activated in the osteocyte upon mechanical loading. The role of estrogen (specifically estrogen loss) in regulation of this pathway in osteocytes is not fully understood. I hypothesize that estrogen is …
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Numerical modeling of cortical bone adaptation due to mechanical loading using the finite element method
… adapts its shape and structure according to its mechanical environment. Bone adaptation occurs on the dense cortical bone and porous trabecular bone. The process of bone adaptation is shown to be dependent on a number of mechanical loading parameters such as magnitude, frequency, number of bouts …
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Mechanical loading-induced and residual stress measurements in transparent spinel ceramics using Digital Gradient Sensing
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-04-12 without embargo terms
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