Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Mecamylamine"”.
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Effects of mecamylamine on nicotine-induced conditioned hyperactivity and sensitization in differentially reared rats
… this study also examined the effects of mecamylamine, an antagonist to nicotinic acetylcholine receptors, on conditioned hyperactivity and sensitization. This antagonistic drug has been shown to attenuate the locomotor effects of nicotine. In the current study, EC, IC, and social …
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Comparison Of Affective Analgesia And Conditioned Place Preference Following Cholinergic Activation Of
… atropine (muscarinic antagonist) and mecamylamine (nicotinic antagonist) into the VTA prior to carbachol treatment. The present study indicates that unilateral carbachol (4 µg/0.25 µl) supports the CPP learning in aVTA and pVTA, but not midVTA. Additionally, both atropine (60 µg/0.25 …
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Effects of Reticular Activation on Long-Term Depression in Primary Visual Cortex of the Long-Evans Rat
… cortical fPSPs. Application of scopolamine and mecamylamine did not restore LTD or prevent the complex oscillatory activity seen in V1. These results show that excitation of the brainstem activating system blocks the induction of LTD in V1. Thus, higher levels of neural activity may inhibit …
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Targeted Disruption of Lynx2 Reveals Distinct Functions for Lynx Homologues in Learning and Behavior
… Nicotine and nicotinic receptor antagonist, mecamylamine, show distinct effects on motor learning in lynx2-/- mice and WT mice. The properties of this new family of lynx1-like molecules, taken together with those of lynx1 and the secreted Ly6SF member SLURP1 (secreted Ly6/UPAR related …
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Neuronal plasticity in the enteric nervous system motor pathways
… receptor blockade using hexamethonium or mecamylamine inhibited peristalsis. 6 out of 20 preparations showed almost full recovery with electrical stimulation at the oral end in the presence of hexamethonium. Peristalsis also showed some recovery when electrical stimuli were applied in the …
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Biochemical aspects of Tourette's Syndrome
… central nicotinic cholinergic receptors, since mecamylamine pretreatment abolished this effect. Conversely, twice daily subcutaneous injections of nicotine for 7 days, led to an increase in spontaneous and DOI-induced HS. Chronic nicotine also caused a significant elevation m plasma and whole …