Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Mebendazole"”.
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The Effect of Mebendazole and RAN Mediated Pathways on Human Breast Cancer Cells
… This study investigated the hypothesis that Mebendazole has anti-cancer activity via Ran and has antiangiogenic effects, which can be repurposed as a therapeutic for breast cancer treatment. Furthermore, the project aims to establish the efficacy of Mebendazole in combination with the known …
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MANIPULATING CELL STATES FOR LEUKAEMIA DIFFERENTIATION THERAPY USING NETWORK PHARMACOLOGY
… their target networks identified dimaprit and mebendazole as a drug combination which induces myeloid differentiation. Alternatively, we show that genetic and pharmacologic manipulation of MOGRIFY-identified TFs, specifically MYC and IRF1, also leads to co-operative induction of differentiation …
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Evaluation of Anthelmintic Properties and Toxicity of Pure Compounds Isolated from Dalea Spp (Plantae, Fabaceae)
… Currently, the benzimidazoles albendazole and mebendazole are used as the primary treatment; however, resistance to these drugs is emerging. Due to this resistance, finding new anthelmintic compounds active against hookworm is a priority. Previously, a pure compound isolated from <em>Dalea …
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Spironucleus Vortens of the Freshwater Angelfish (Pterophyllum scalare): Growth Requirements, Chemotherapeutants, Pathogenesis and Immunity
… pyrimethamine, albendazole, fenbendazole, mebendazole, and magnesium sulfate was evaluated. The pathogenicity of S. vortens in angelfish was investigated in fish experimentally inoculated with trophozoites. This study provided information to help understand the pathogenesis of the parasites …
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Διερεύνηση των επιπέδων κτηνιατρικών ανθελμιθικών ουσιών στο γάλα και εκτίμηση της πρόσληψης από τον άνθρωπο
… οι ουσίες, Albendazole, Febantel, Fenbendazole, Mebendazole και κάποιοι μεταβολίτες τους (Albendazole sulfoxide, Albendazole sulfone, Fenbendazole sulfone) στο νωπό γάλα προβάτων, αιγών και βοοειδών. Μέθοδοι: Χημική ανάλυση δειγμάτων γάλακτος, με τη βοήθεια Υγρής Χρωματογραφίας Υψηλής Απόδοσης …
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The effect of RAN inhibition on human colorectal cancer cells (CRC)
… to assess the hypothesis that the Ran inhibitor mebendazole MBZ reduces cell invasion and metastasis of CRC. I have investigated MBZ effect on the CRC isogenic human cell lines with specific mutations (HCT-116 K-Ras, DLD-1 K-Ras and Pten deletion and wild type HCT-116 and DKO-3. I used qRT-PCR …
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In vitro anti-cancer effects of benzimidazoles on the canine osteosarcoma D17 cell line
… the clinically-used veterinary benzimidazoles [mebendazole (MBZ), fenbendazole (FBZ), and albendazole (ABZ)] on a canine OS cell line. Cell lines were evaluated for dose-dependent anti-neoplastic effects on the functions of cell proliferation, cell-cycle phase distribution, and cell death. …