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Showing 1 to 20 of 21 for “"Mean Residence Time"”.
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Exploration of parameters for the continuous blending of pharmaceutical powders
… fill fraction, the number of blade passes, the mean residence time, the Bodenstein number, and the period of input feed fluctuations. The results highlight the importance of shear and radial mixing for cohesive powders, which suggest that one-dimensional axial models common in blending …
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Mixing in granular systems and applied coating technology
… in rotary drum mixers. Rotary mixers are prime means for creating such coatings. Continuous mixers are preferred over batch models, in order to obtain high production volumes. The mixing time is difficult to predict in a continuous process, whereas in a batch system it is easily controlled. The …
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Investigation of Melt Electrical Conductance in Food Extrusion
… the feed rate and the screw speed decreased the mean residence time but the feed rate effect was more pronounced. The specific feeding load, barrel fill and flow profile were affected by the feed rate and the screw speed in opposite directions. Spread of the normalized RTD decreased with …
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An analysis of microbial film fermentor system for production of secondary metabolites
… the optimum inlet substrate con- centration and mean residence time were found to be 20 (g glucose/liter) and 10 (hours), respectively. Production phase could be extended by increasing the substrate concentration in the feed stream, but the optimum increasing rate and initiation time of increase …
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Carbon dioxide emissions from selected soils in Zambia : effects of nitrogenous fertilizer and agricultural lime.
… soils ranged from 378 to 543 mg C/kg soil with a mean of 473 mg C/kg soil. The mean seasonal carbon mineralization rate across soils was 0.043 or 4.3 %. Non statistically significant differences were observed between mean seasonal CO2-C emissions of soils with amendments and those of the control. …
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CHARACTERIZATION OF INDIVIDUAL CHARGED Au25(SG)18 CLUSTERS AND THEIR ENHANCEMENT OF SINGLE MOLECULE MASS SPECTROMETRY
… where the clusters are shown to increase the mean residence time of polyethylene glycol (PEG) molecules within an alpha hemolysin (αHL) nanopore. The effect appears over a range of PEG sizes and ionic strengths. This increases the resolution of the peaks in the single molecule mass …
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Engineering aspects of calcium carbonate and magnesium hydroxide precipitation in waste water reclamation
… and magnesium hydroxide precipitation are time dependent. As a consequence of this time dependency unstable effluent may be produced under reaction conditions commonly encountered in practice. An exhaustive study identified the major factors affecting the precipitation kinetics. Reaction …
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Continuous blending of dry pharmaceutical powders
… powders coupled with long quality analysis times increases the production cycle time leading to strained cash flows. Also, scale-up issues faced in process development causes delays in transforming a drug in research to a drug under commercial production. Continuous blending is as an …
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Tracer-Independent Approaches to Stratosphere-Troposphere Exchange and Tropospheric Air Mass Composition
… thermal tropopause according to stratospheric residence time τ and the regions where air enters and exits the stratosphere, the one-way flux is quantified robustly without being rendered ill-defined by the short-τ eddy-diffusive singularity. Diagnostics are first computed using an idealized …
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Groundwater/surface water interaction in the Raisin River watershed, near Cornwall, Ontario.
… on the site. Seepage flux ranges from $2.23\times10\sp{-6}$ to $\rm{-}9.82\times10\sp{-9}m\sp3m\sp{-2}s\sp{-1},$ and hydraulic conductivity ranges from 10$\sp{-6}$ to 10$\sp{-9}$ ms$\sp{-1}$ (a negative seepage flux indicates groundwater flow from the aquifer to the river). Environmental …
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Prodrug Approach to Improve Oral and Brain Absorption of HIV Protease Inhibitor, Lopinavir
… higher compared to LPV in rats. Moreover, mean residence time of prodrugs was significantly higher compared to LPV indicating that prodrugs may stay for a longer time period in plasma. Prodrugs were observed to possess lower binding affinity towards plasma proteins. Di-peptide prodrug …
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Constructed Floodplain Wetland Effectiveness for Stormwater Management
… that wetland hydrology existed on the site. The mean residence time of the wetland was found to be 100 min for flow-rates of 4.25-5.1 m3/min. Residence time distributions of the high and low marsh features identified a considerable degree of flow dispersion. Manning's n varied between …
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Effect of rutaecarpine on caffeine pharmacokinetics in rats
… or they avoid drinking them close to bedtime to prevent caffeine from interfering with their sleep. Ruta Cleanse and Ruta Sleep are natural supplements containing rutaecarpine that are designed to speed up the removal of caffeine from the blood. The recommendation is to take two capsules …
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Understanding bulk behavior of particulate materials from particle scale simulations
… particle processing devices. For comil, the mean residence time (MRT), spatial distribution of particles, along with the collision dynamics between particles as well as particle and vessel geometries are examined as a function of the various operating parameters such as impeller speed, screen …
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The development of a mathematical model for the bioextraction of the critical raw material magnesium from mine waste using acidithiobacillus caldus
… the high-impacting param-eters: pH and mean residence time. Implementation of a two-stage system allowed for the independent optimisation of the microbial oxidation stock (Vs), and mineral (V1) reactors. Using the previously de-termined mineral reactor conditions (0.5% solids loading, τ1 …
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Pharmacokinetics and Effects on Blood Chemistry of Cyclosporine in Human Infants and Kid Goats
… later an oral cyclosporine dose of 20 mg/kg. The mean area under the concentration-time curve (AUC) IV was 1920 ± 208 ng-hr/mL (SEM) versus oral 6210 ± 685 ng-hr/mL . The IV mean residence time (MRT) was 2.1 ± 0.1 hr with a calculated half-life of 1.6 ± 0.1 hr as compared to the oral MRT 15.1 hr …
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Characterization of Post-translational Modifications and Resulting Structure/Function Relationships of Recombinant Human Factor IX Produced in the Milk of Transgenic Pigs
… half-life. From this study it was found that the mean residence time of tg-FIX after injections is approximately twice that observed for pd-FIX. These altered pharmacokinetic properties are likely linked to the unique tg-FIX PTM structure, perhaps through altered endothelial cell binding …
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Incorporating Recent Geochemical and Isotopic Constraints in Age Dating the Waters of Hot Springs National Park, Arkansas
<p>Mean water age for spring discharge in Hot Springs National Park was calculated as approximately 4,400 years by Bedinger et al (1978) using carbon-14. Their analysis indicated that the water was a mixture of a small portion of cold water that was less than twenty years old with a preponderance …
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Turbulent Exchange of Ozone and Nitrogen Oxides between an Amazonian Rain Forest and the Atmosphere
… ozone fluxes above the Amazonian rain forest. Mean daytime maxima of -11.0 nmol m^(-2) s^(-1) and 2.3 cm s^(-1) for ozone flux and deposition velocity, respectively, show the rain forest to be an effective sink for ozone during the wet season. At the end of the dry season, under conditions of …
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Diagnostic analysis of runoff partitioning at the catchment scale
… generated runoff. Dimensionless flood peak and time-to-peak are used to explore the advection and dispersion separately. The results in this work are on the one hand consistent with previous theoretical studies, and on the other hand also somewhat surprising. For example, the power-law …
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