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Showing 1 to 2 of 2 for “"Mdn1"”.
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Chemical Biology, Biochemical and Structural Studies of MDN1, an AAA Protein Required for Ribosome Biogenesis
… the precursors of ribosomes at fast time scales. Mdn1 is an essential dynein-like AAA protein (ATPases Associated with various Activities) that releases specific assembly factors from the precursors of 60S subunit of ribosomes. However, Mdn1's unusually large size (~5000 amino acids in a single …
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A STRUCTURAL AND FUNCTIONAL ATLAS OF THE HUMAN RIXOSOME COMPLEX
… NOL9 (RNA kinase), SENP3 (SUMO protease), and MDN1 (AAA+-ATPase motor). The rixosome also has conserved RNA processing functions at heterochromatin, effectively triggering polycomb gene silencing. It has become increasingly clear that the seven protein members of the rixosome stably associate …