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Showing 1 to 20 of 117 for “"Matrix-assisted-laser desorption/ionization"”.
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MICROFLUIDIC DYNAMIC ISOELECTRIC FOCUSING COUPLED TO MATRIX ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRY
… to the current demands of proteomics studies. Matrix assisted laser desorption/ionization (MALDI) mass spectrometry has evolved into a primary analytical tool for proteomics research. MALDI is fast and efficient and has a high tolerance to non-volatile buffers and impurities. The samples for …
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TARGET MODIFICATION FOR ENHANCED PERFORMANCE MATRIX ASSISTED LASER DESORPTION IONIZATION (MALDI) MASS SPECTROMETRY
… TARGET MODIFICATION FOR ENHANCED PERFORMANCE MATRIX ASSISTED LASER DESORPTION IONIZATION (MALDI) MASS SPECTROMETRY MAJOR PROFESSOR: Dr. Gary R Kinsel MALDI MS, a powerful tool for the analysis of biomolecules, has undergone major advancement in instrumentation to yield improvements in …
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Matrix-assisted laser desorption/ionization mass spectrometry for the analysis of collected bioaerosols
… of microorganisms from bioaerosols using offline matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) for the analysis of proteins. MALDI-MS intact bacteria techniques were adapted for use with an orthogonal MALDI quadrupole-time-of-flight mass spectrometer. Results indicate …
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Neurochemical detection in small volumes by matrix-assisted laser desorption/ionization mass spectrometry
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-08-01
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Investigation of Phosphatidylinositols and Phosphoinositides Using Matrix- Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is a powerful analytical technique that captures the spatial distribution of biomolecules directly from tissue surfaces. Widely used in lipidomics, MALDI-MSI provides label-free, high-resolution imaging of lipid …
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DEVELOPMENT OF A NOVEL MATRIX ASSISTED LASER DESORPTION / IONIZATION (MALDI) BASED PEPTIDE QUANTITATION APPROACH
Matrix Assisted Laser Desorption / Ionization (MALDI) Mass Spectrometry (MS) has emerged as an important tool in the field of proteomics mainly because it is simple, quick and efficient. The identification and quantitation of biomarkers, protein targets for drugs, and metabolites are some of the …
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Advancements in matrix-assisted laser desorption ionization mass spectrometry of peptides, proteins and polymers
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1998.
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Optimization of sample preparation in Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry of macromolecules
<p>New method for the matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) and Fourier transform mass spectrometry (MALDI-FTMS) analysis of low molecular weight polyvinyl acetate (PVAc) was developed and then applied to the characterization of commercially available chewing gum. …
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High-throughput matrix-assisted laser desorption/ionization mass spectrometry for single-cell and single-organelle measurements
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-12-04 without embargo terms
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Identification and Characterization of Bacterial and Bacteriophage Proteins Via Matrix-Assisted Laser Desorption Ionization (Maldi) Mass Spectrometry
… have emerged. Here, it is shown how using matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry, coupled with sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), one can identify and characterize bacterial and bacteriophage proteins.</p>
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De novo peptide sequencing from matrix-assisted laser desorption/ionization-time of flight post-source-decay spectra
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2001.
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Oligosaccharide Analysis via Anion Attachment Using Negative Mode Electrospray (ES) and Matrix Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry
Eleven tested anions were able to form adducts with neutral oligosaccharides at low cone voltage in negative ion mode electrospray mass spectrometry. Among them, fluoride and acetate have the abilities to significantly enhance the absolute abundance of [M-H]- for neutral oliogosaccharides. The …
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MATRIX-ASSISTED LASER DESORPTION/IONIZATION (MALDI) TARGET MODIFICATION FOR ENHANCED PROTEOMICS ANALYSIS AND PLASMA POLYMER CHARACTERIZATION BY MALDI MASS SPECTROMETRY
… available for incorporation within the MALDI matrix. In the presented studies MALDI targets are modified with polyethylene glycol (PEG)-like structures via chemical grafting of PEG onto polyurethane (PU) film and rf plasma polymerization of ethylene oxide vinyl ether (EO2) and tetraglyme. It …
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DARK-PIGMENTED, AMOXICILLIN-RESISTANT, BACTERIAL SPECIES IN CHRONIC PERIODONTITIS MICROBIOTA IDENTIFIED WITH MATRIX ASSISTED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT MASS SPECTROMETRY.
… colonize and inhabit human subgingival sites. Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry and its associated analytic software, was recently approved for clinical microbiology diagnostic use in the United States by the United States Food and Drug …
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Detection and Imaging of Neurotransmitters in Rodent Brain Tissue Using FMP-10 and ZnO Nanoparticle Matrices with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) is an analytical technique used to visualize the spatial distribution of molecules within biological samples. In our lab, we employ two complementary matrices, 2-fluoro-1-methyl pyridinium (FMP-10) and zinc oxide …
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Microseparation Strategies for the Assay of Neuronal Samples
… described here are the culmination of HPLC, matrix assisted laser desorption ionization (MALDI) time-of-flight mass spectrometry, and molecular biology techniques to quantify and characterize the novel peptides.
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Peptide Analysis Using Capillary Electrophoresis With Fluorescence Detection
… are presented for combining this method with matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) for the identification of unknown peptides.
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