Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Matrix metalloproteinase inhibitor"”.
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Pharmacological investigations into matrix metalloproteinase-activated anti-tumour prodrugs. In vitro metabolic and pharmacological investigations into a series of colchicine-based peptide prodrugs activated by tumour-expressed matrix metalloproteinases
Matrix metalloproteinases (MMPs) play a significant role in degrading the extra- cellular matrix in cancer development and metastasis. Overexpression of matrix metalloproteinases in tumour tissues relative to normal tissues has been exploited as a target for peptide-based therapeutics, to improve …
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Impact loading and functional tissue engineering of articular cartilage
… with the polymer P188, growth factor IGF-I, or matrix metalloproteinase inhibitor doxycycline partially ameliorated cell death and sGAG loss, two detrimental changes that occurred following either Low or High impact. With 1 week of treatment after Low impact, P188 reduced cell death 75% and …
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Identifier et traiter la tendinopathie modérée des tendons de queue de rat ex vivo
Contexte: La tendinopathie, une condition générale qui affecte le tendon, est fréquente, spécialement chez les athlètes et les travailleurs. La tendinose, une dégénérescence du tendon sans inflammation, est une forme fréquente de tendinopathie qui peut être chronique et difficile à traiter à long …