Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Matrix Metalloproteinase-1"”.
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Functional Consequences of Matrix Metalloproteinase-1 Over-Expression in Human Gliomas
… to their ability to invade surrounding tissue. Matrix metalloproteinases are thought to contribute to the invaseive phenotype of human gliomas. Absent in normal brain, matrix metalloproteinase-1 (MMP-1) has been shown to be present in gliomas, and in particular in glioblastoma multiforme (GBM). …
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The Influence of a Single Nucleotide Polymorphism In The Matrix Metalloproteinase-1 Promoter on Glioma Biology
… responsible for this invasive nature include the matrix metalloproteinase family. MMP-1 is a member of this family which has been well studied in many types of invasive tumors, with gliomas being an exception. We studied a single nucleotide polymorphism (SNP) in the MMP-1 promoter that may …
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Investigating novel therapeutic targets for treatment of visceral pain.
… of inflammatory mediators (angiotensin II and matrix metalloproteinase 1) upregulated during colitis on colonic afferent activity. Pre-treatment with NS 1619, an opener of BKCa (subtype of KCa channels) had no effect on the colonic afferent response to ATP. Similarly, the combined IKCa/SKCa …
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Smoking and High-Fat Diet: Risk Factors Regulating Emphysema Formation
… to the degradation of the extracellular matrix, ultimately resulting in emphysema. Studies in chapters three and four show that hypercholesterolemia is an important risk factor for pulmonary emphysema. These studies discuss the role of MAP kinases, Toll-like signaling, ceramide signaling …
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Documentation, anti-aging activities and phytochemical profiling of selected medicinal plants used by Jakun women in Kampung Peta, Mersing, Johor
… been tested on the three formulations which are matrix metalloproteinase-1 (MMP-1) inhibition, elastase inhibition, tyrosinase inhibition, acetyl- and butyrylcholinesterase inhibition assays. Single formulation of U. micrantha showed the highest inhibition towards MMP-1 (49.44 ± 4.11 %) and …
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The Therapeutic Potential of Natural Products from <i>Vaccinium</i> Berries for Viral and Lung Diseases Through an Improved LC-MS-Based Chemometric Approach
… downregulating proteolytic enzyme collagenase matrix metalloproteinase-1 (MMP-1). In contrast, procyanidin dimer A2 induced inflammation alone. Furthermore, jaboticabin, an anti-inflammatory depside, was found in several <em>Vaccinium</em> berries for the first time.</p> <p>Procyanidins have …