Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Matriptase"”.
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Matriptase Mediated C-Met Signaling In Breast Cancer
<p>MATRIPTASE MEDIATED c-MET SIGNALING IN CRITICAL FOR BREAST CANCER PROGRESSION </p> <p>by</p> <p>GINA ZORATTI</p> <p> Historically proteases have been associated with tumor progression and metastasis through degradation of the basement membrane. However, in recent years these enzymes have also …
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Étude du clivage de l'hémagglutinine de l'influenza par la matriptase
… de type II (TTSP), particulièrement de la matriptase, a été explorée. Les résultats obtenus démontrent que la matriptase et plusieurs autres enzymes du groupe des TTSP sont exprimées dans l'épithélium bronchique humain. La matriptase et d'autres TTSP peuvent cliver des peptides …
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Role of matriptase in the regulation of epithelial barrier permeability studied using MDCK cells
The!typeNII!transmembrane!serine!protease!matriptase!plays!an!important!role!in! the!integrity!of!epithelial!barriers.!However,!the!molecular!mechanisms!underlying! the!role!of!matriptase!are!unknown.! To! study! these!mechanisms,! two!variants!of!MadinNDarby!canine!kidney!(MDCK)! cells!were! …
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Matriptase/pdgf D/beta-Pdgfr Signaling Axis In Human Prostate Cancer: The Role Of Pten In The Regulation Of Pdgf D Expression
… and bone metastases, we found that PDGF D and matriptase are associated with prostate cancer progression. Additionally, in a clinically relevant prostate-specific PTEN (phosphatase and tensin homolog) knockout mouse model, we found an increase in PDGF D expression and ?-PDGFR phosphorylation …
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The development of novel strategies to modulate epithelial sodium channel (ENaC) activity in chronic obstructive pulmonary disease (COPD)
… human airway trypsin-like (HAT) protease, matriptase, and prostasin. QUB-2136 was capable of inhibiting amiloride short-circuit current to a greater extent and for a longer period of time when compared to QUB-1916. However, further evaluation of QUB-2136 indicated that structural …