Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Matrin3"”.
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Protein misfolding toxicity and inclusion formation in cellular models of neurodegeneration
… Rho Guanine Nucleotide Exchange Factor (RGNEF), Matrin3, which are involved in amyotrophic lateral sclerosis (ALS) and polyglutamine (polyQ) expanded huntingtin, which causes Huntington’s disease (HD). Genetic, biochemical, and pathological findings implicate RGNEF and Matrin3 in Amyotrophic …
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Commonalities between SMA and ALS: investigation of ribosome heterogeneity and translational defects
… the RBPs TAR DNA binding protein 43 (TDP43) and Matrin3 (MATR3), involved in ALS, are associated with the translation machinery. In addition, translatome changes are commonly observed in both diseases and loss of SMN and dysregulation of TDP43 and MATR3 are associated with translation defects of …