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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 31 for “"Maternal diet"”.
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Maternal diet and programming of embryo and fetal development in the mouse
… study examined the impact of a relatively mild dietary protein restriction in the mouse during pregnancy on the subsequent development of the fetus. The responses of the fetus to the maternal dietary challenge were studied close to the end of gestation (at day 17) using three broadly different …
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The impact of suboptimal maternal diet on fetal heart development: Identifying targets for intervention
… pig) to understand how exposure to a suboptimal diet (under- and overnutrition) at different timings, severities, and durations impacts growth, hormonal, metabolic, and contractile profiles within the fetal heart. Across studies, it was highlighted that high-risk cardiac phenotypes are present …
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Effect of maternal dietary fats on growth rate and bone development of commercial broilers
The effect of maternal dietary fats on growth rate and bone development of commercial broilers was examined. Addition of fats [soybean oil (SBO), menhaden oil (MO) and chicken fat (CF)] to the maternal diet altered the tissue and yolk composition of the hens to reflect the dietary fat source. …
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Effects of Maternal Dietary Fats and Antioxidants on Growth Rate and Bone Development of Commercial Broilers
The effect of maternal dietary fats on growth rate and bone development of commercial broilers was examined. Three hundred fifty female chicks were winged banded, weighed and equally divided among six starter pens (1.52 X 3.66m) with litter floors. At 20 wk of age, each pen was fed a basal laying …
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Maternal High Fat Feeding: Impact of Female Offspring Body Composition and Bone Health
High fat diet (HFD) consumption in rodents alters body composition and weakens bones. Whether female offspring of mothers consuming a HFD are similarly affected at weaning and early adulthood is unclear. This research determined whether maternal HFD contributes to long-lasting alterations in body …
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Dietary Effects of Selenium During Reproduction in the Rat (Lactation, Milk, Pregnancy, Bioavailability, Glutathione Peroxidase)
… Research Council (NRC) has recommended a dietary selenium (Se) concentration of 0.1 ppm for the laboratory rat. This dietary level produced maximal liver glutathione peroxidase (GSH-Px) activity in growing male rats. Similar studies were not performed in female rats during growth or …
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Impacts of maternal dietary fat intake on fetal development in an ovine model
Maternal diet during pregnancy can influence fetal development and may have lasting effects on offspring health and disease risk trajectory. Intake of dietary fatty acids has been a major focus in the biomedical and epidemiological literature given concerns about the adverse effects of excessive …
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The effects of diet varying in fat content on the pathogenesis of diabetes mellitus in wistar rat offspring
… peripheral insulin resistance. Studies show that maternal health directly influences foetal development and birth outcomes. Malnutrition of the growing foetus may lead to development of T2D and other metabolic diseases later in life. Consequently, several studies have reported that maternal diet …
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Investigating the molecular mechanisms of the metabolic syndrome
… rat model developed through manipulation of the maternal diet to provoke the key features of the metabolic syndrome in adult o spring. Microarray technology was used to detect changes in gene expression in tar- get tissues between o spring of control (normally fed, AD) and undernourished (UN) …
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The Effects of Dietary Lipids on Bone Chemical, Mechanical and Histological Properties in Japanese Quail (Coturnix C. Japonica)
… to evaluate the effects of supplementing diets with different lipids on bone chemical, mechanical, and histological properties. In Exp. 1, laying hens were fed a basal diet containing either 5% soybean oil (SBO), hydrogenated soybean oil (HSBO), chicken fat (CF), or menhaden fish oil (FO). …
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Insights into determinants of cancer susceptibility, initiation, and progression:studies on medulloblastoma and Histiocytic Sarcoma in mouse models
… presents a discussion of both perigestational dietary influence on cancer predisposition as well as somatic genetic determinants of cancer development. Both projects used genetically engineered mouse models of cancer. The introductory chapter gives a brief historical introduction to cancer, …
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A study of the association of prenatal inflammatory diet and adverse infant birth outcomes in a birth cohort in Uganda
… conditions has recently been linked to maternal diet during pregnancy. As such it has been important to study the role of maternal diet during pregnancy to find any association with maternal and infant outcomes. Highly diverse diets have been thought to be a proxy to maternal nutrient …
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An investigation into whether an exercise intervention during pregnancy can prevent the programming of cardiovascular disease in the offspring of obese mothers
… many years to come. Adverse exposures, such as maternal overnutrition, in the early life environment increase the risk of traditionally adult-onset diseases such as cardiovascular disease and type 2 diabetes adding greatly to the next generation’s burden of disease. Studies in animal models …
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Leptin and peroxisome proliferator activated receptor alpha: understanding their contribution towards normalising the programmed phenotype in the peripheral tissues of IUGR offspring
… growth restriction (IUGR) induced by maternal global undernutrition, adult offspring are obese with associated metabolic disturbances. These metabolic abnormalities are all augmented by feeding a high calorie postnatal diet and reversed by neonatal leptin treatment. Evidence is now …
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The effects of different iodine availabilities on thyroid function during development in Japanese quail
… during development. Low (≤50 μgI/kg feed in the maternal diet) and high (1200 μgl/kg feed) I availability were compared to control levels (800 μgI/kg feed). Thyroid gland (TG) content of I, triiodothyronine (T3), and thyroxine (T4), plasma concentrations of T3 and T4, and hepatic 5’ …
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Exploring the impact of maternal obesity on offspring renal morphology and later life health
… environments in early life including both maternal under and over-nutrition predisposes individuals to similar adverse traditionally adult onset diseases such as the metabolic syndrome. Epidemiological observations and animal models have highlighted that early life exposure to maternal …
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The Impact of Excess Nutrients, Fatty Acids or Glucose, on BeWo Placental Trophoblast Metabolic Function
… nutrients in pregnancies complicated by maternal obesity and diabetes mellitus has been well linked with the development of metabolic health disorders in the exposed offspring. Impairments in placental development, mitochondrial respiration, and nutrient processing are thought to …
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Maternal programming of piglet microbiomes
Understanding how maternal factors in early life influence piglet microbiomes is key to unlocking the potential for manipulation of these factors to positively influence pig health and production without the need to resort to individualized interventions such as dietary antimicrobials later in …
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Understanding factors affecting tendon healing: Characterising the role of obesity on tendon healing and homeostasis and augmenting its effects with growth factors
… and economic impact of rotator cuff tears. Diet-induced obesity (DIO) in rodent models were used to investigate obesity’s effects on tendon homeostasis and healing after surgery and understand the impact of maternal diet on adult offspring tendon properties. The influence of body mass index …
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Fetal origins of cardiovascular dysfunction in an ovine model of maternal obesity in pregnancy
… gap, we generated a novel ovine model of maternal diet-induced obesity during pregnancy to investigate its impacts on fetal cardiovascular physiology. We adopted an integrative approach, combining experiments of fetal cardiovascular function in vivo following surgical instrumentation with …
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