Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 31 for “"Maternal Separation"”.
-
Mothers’ lived experience of maternal separation: a phenomenological exploration
There is little literature on the topic of maternal separation from an existential philosophical perspective. An existential-phenomenological approach provides a thorough and organised analysis of maternal separation by examining the various aspects of human experience, including the physical, …
-
The Effect of Maternal Separation and Postnatal Oxytocin Administration on Social Recognition in Adolescent Female Mice
… of literature indicates that exposing rodents to maternal separation during infancy results in long - term developmental changes in physiological, behavioral, and psychological domains. Because several previous studies have indicated that maternal separation may be detrimental to the processing …
-
Maternal separation in the rat : long-term effects of early life events on emotionality, drug response and neurobiology
… investigate early experiences. In the rat, maternal separation of pups in early ages have been linked to anxiety-related behavioral, endocrinological and neurochemical disruptions in the rat. The aim of the thesis was to investigate these proposed disruptions in pups exposed to repeated …
-
Effect of maternal separation on stress-related proteins measured in a 6-hydroxydopamine rat model of Parkinson’s disease
The developing central nervous system is especially vulnerable and research has implicated early life stress (ELS) as a potentiating factor to cell death in a rat model of Parkinson’s disease (PD). PD is a movement disorder resulting from the selective degeneration of dopamine neurons in the …
-
Effects of decreasing maternal separation of under 6-month old infants directly before and after surgery on allostatic load and outcomes : a randomised control trail [i.e. trial]
… is that infants below six months old do not show separation anxiety (Bretherton, 1985). The objective of the study was to measure the evidence of stress using heart rate variability and impedance cardiograph as indicators of autonomic nervous system activation in order to determine whether …
-
Effetto della separazione materna sulla plasticità dei neuroni nell’ippocampo delle mamme e della prole
… resilience to stress. Post-natal stress, such as maternal separation, have a deep impact not only for the offspring, but also for mothers, and lead to neuroendocrine, behavioral and structural changes in the brain. Neuroplasticity was evaluated both in mothers and offspring. Mothers were killed 21 …
-
Neonatal Maternal Separation and Alcohol Abuse in C57BL/6J mice: A Study of the Functional Alterations of GABAergic and GLUergic Systems and the Possible Protective Role of Esterogen
… we investigated the effects of neonatal repeated maternal separation (RMS) on alcohol abuse in adult C57BL/6J mice and potential functional alterations of GABAergic and GLUergic systems in different brain areas. Male animals subjected to RMS consumed significantly higher amount of ethanol when …
-
Linking child care to infant attachment : what lies in-between?
… To investigate the relationship between maternal separation anxiety, hours in non-maternal child care and security of motherinfant attachment in early infancy. <br></br><br></br>Design: Prospective. Methods: The participants for this study were 67 mothers and their infants enrolled in a …
-
The Impact of Early Life Adversity on Mediodorsal Thalamic-Prefrontal Cortex Maturation
… is mediated by local GABA- AR. Following P2-20 maternal separation ELA, the facilitation pattern and suppression patterns were attenuated. Interestingly, rats exposed to P2-10 maternal separation ELA showed normal facilitation and suppression patterns. However, rats exposed to P11-20 maternal …
-
Novel insights into the role of the GABAB receptor in depression and anxiety
… alone or in combination with early-life stress (maternal separation), in modulating antidepressant like and anxiety-related behaviours. Pharmacological blockade of the GABAB receptor with CGP52432 had antidepressant-like behavioural effects. Moreover, mice lacking the GABAB(1b) receptor subunit …
-
Alterations of the Corticotropin Releasing Hormone Receptor System Following Early Life Stress and Ethanol Self-Administration in Rhesus Monkeys
… binding. We used an accepted ELS model of maternal separation with nursery-reared (NR) and mother-reared rhesus monkeys induced to self-administer EtOH or control solution for over 12 months. Subjects underwent endocrine challenges to probe the HPA axis before and after drinking. Brains …
-
The effects of early developmental stress and exercise intervention on neurodegeneration in a rat model of Parkinson's disease
… axis activity. Animal studies have shown that maternally separated rats exhibit increased anxiety- and depression-like behaviour in adulthood, although other evidence shows hyperactivity and impulsivity in such cases. Given that stress has these behavioural effects, it is of interest to …
-
Factors influencing the psychological adjustment of young patients with Type 1 diabetes in the first year after diagnosis
… as metabolic control (McDonnell et al., 2007), maternal functioning (Schmidt, 2007) and protective parenting (Mullins et al., 2004). Parenting factors may have an impact on young children (Whittemore et al., 2003; Davis et al., 2001); while other factors such as self-efficacy are important to …
-
Relational Spirituality and Maternal Coping in Carceral Contexts: A Participatory Action Study of Meaning-Making and Mental Health Among Formerly Incarcerated Mothers
<p>Maternal incarceration carries significant psychological, familial, and community consequences, yet limited research centers the mental health experiences of mothers themselves. This study explored how religious and spiritual engagement shape mental health and coping among formerly incarcerated …
-
Exploring the neurobehavioural impacts of combined early life and adult stress on decision making under uncertainty
… of early life stress (ELS) using the repeated maternal separation (MS) procedure in rats. The specific hypothesis tested was that stress effects accumulate over the developmental lifespan, resulting in either stress resilience or vulnerability in adulthood. Early postnatal life is a critical …
-
Behavioural, immunological, and neurobiological effects of early life stress in rats
… stress itself. To do this, I used the repeated maternal separation (RMS) model of chronic early life stress, and I focused particularly on those effects of possible relevance to anxiety, depression, and inflammation-related physical disease. In Chapter 3, I describe the long-term effects of RMS …
-
The effect of voluntary exercise on adult hippocampal neurogenesis in maternally separated rats
Maternal separation (MS) has been shown to produce depression-like symptoms in male Sprague Dawley rats. The underlying mechanisms responsible for the development of these depression-like behaviors are unknown. However, a growing body of evidence suggests that a reduction in neurogenesis may be a …
-
Investigating the molecular underpinnings of major depressive disorder and the utility of biomarkers in the inflammatory cytokine pathway as aids for clinical diagnosis and treatment selection
… the transcriptional effects of maternal separation. The top stress by<br/>strain interaction was found in the telomerase RNA component gene (Terc). We<br/>also found that a single nucleotide polymorphism in TERC (rs10936599),<br/>previously identified as a predictor of telomere …
-
The effect of exercise on spatial learning and hippocampal proteins in maternally separated adult rats
Repeated maternal separation (MS) has been reported to induce changes in hypothalamic-pituitary- adrenal (HPA) axis activity leading to abnormal stress responses later in life. Such alterations have also been linked to poor cognitive function. In contrast, exercise enhances cognitive function. …
-
LNX1 and LNX2 in the central nervous system: linking behavioural, cellular and molecular perspectives
… in altered pup ultrasonic vocalisation following maternal separation and reduced body weight. To further examine the potential role of Lnx1p70/p62 in growth and early development, Chapter 3 revealed a disruption of pruning and maturation of hippocampal CA3-mossy fiber synapses in Lnx1p70 deficient …
Page 1 of 2