Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"Maternal HIV"”.
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The impact of maternal HIV infection on uninfected neonate brain structure
Successful prevention of mother-to-child HIV transmission (PMTCT) programs have reduced the risk of infant HIV infection in South Africa from 8% in 2008 to an estimated 1.4% in 2015, resulting in an increasing population of HIV-exposed uninfected (HEU) children. However, the long-term effects of …
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Assessing the cost-effectiveness of national Kenyan repeat maternal HIV testing guidelines
… 95-95-95 goals for prevention of mother-to-child HIV transmission (PMTCT) by 2030; yet, each year there are 13,000 new infant HIV infections. Repeat testing in the third trimester and in the postpartum period, when risk of HIV acquisition is high, can help detect and treat incident maternal …
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The influence of maternal HIV status on mortality in children under the age of five years
… to 25 deaths by 2030 (United Nations 2015). HIV/AIDS is one of the leading causes of mortality in Zambia and has contributed to the slow decline of under-five mortality (Garenne and Gakusi 2006). Children under the age of five years get infected with HIV mainly through vertical transmission …
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The influence of maternal HIV and ART exposure on neonate brain white matter integrity and organisation
… cohort of children who have in utero exposure to maternal HIV, but remain HIV negative through the use of antiretroviral therapy (ART), known as HIV exposed-uninfected (HEU) children. While HEU infants and children are healthier than their infected peers, they experience some developmental delays …
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The association of maternal HIV status during pregnancy on longitudinal neuro-immune regulation, and neurodevelopment in HIV-exposed uninfected children
… that the Human Immunodeficiency Virus (HIV) and its effects, such as its impact on the immune system and then the numerous consequences on other biological systems including the central nervous system (CNS), have had a significant effect worldwide. This is particularly relevant in South …
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The association between maternal HIV and stillbirths in an era of universal art in pregnancy in the Western Cape, South Africa
… rates. SSA also faces the highest global HIV prevalence at 20%. South Africa, home to 8.4 million people living with HIV, grapples with a 30% prevalence among pregnant individuals. Antiretroviral therapy (ART) coverage for pregnant individuals reached 97% in 2019, especially in the Western …
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The association between maternal HIV and stillbirths in an era of universal art in pregnancy in the Western Cape, South Africa
… rates. SSA also faces the highest global HIV prevalence at 20%. South Africa, home to 8.4 million people living with HIV, grapples with a 30% prevalence among pregnant individuals. Antiretroviral therapy (ART) coverage for pregnant individuals reached 97% in 2019, especially in the Western …
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Association between infant feeding practices and infant growth by maternal HIV and antiretroviral therapy status: A prospective study in Cape Town, South Africa
Background Infants who are HIV-Exposed Uninfected (HEU) may experience adverse growth outcomes compared to those who are HIV Unexposed Uninfected (HUU). Breastfeeding (BF) provides infants with the necessary nutrients to grow optimally irrespective of maternal HIV status. The initiation and …
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A longitudinal analysis of the completeness of maternal HIV testing, including repeat testing, during pregnancy, and the predictors thereof, in Mitchell’s Plain, Cape Town
HIV testing during pregnancy is the gateway to the HIV-related services that are part of the prevention of mother-to-child transmission (PMTCT) cascade. The virtual elimination of vertical HIV transmission cannot be achieved without universal antenatal care (ANC) HIV testing. Furthermore, women are …
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HIV-positive African women’s engagement with HIV care in the UK during and after pregnancy
Approximately 1400 HIV-positive women are known to become pregnant in the UK each year, the overwhelming majority being from Sub-Saharan Africa. The overall question I pose in this thesis is: how do African women living with HIV in the UK engage with HIV services and interventions during and after …
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The short-term outcomes of HIV-exposed versus HIV-unexposed very low birth weight infants
Introduction: HIV exposed but uninfected infants have been shown to have a higher morbidity and mortality than unexposed infants. There is almost no literature comparing the short-term outcomes of HIV exposed versus unexposed VLBW neonates who are born prematurely. Methods: A retrospective review …
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The Impact of GB Virus C co-infection on Mother to Child transmission of Human Immunodeficiency Virus
… that can inhibit human immunodeficiency virus (HIV) replication in vitro. Persistent coinfection with GBV-C has been associated with improved survival among HIV-infected adults while loss of GBV-C viremia has been associated with poor survival. If GBV-C does inhibit HIV replication, it is …
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Influence of maternal human immunodeficiency virus (HIV) and antiretroviral (ARV) drugs on neonate neurometabolism.
The human immunodeficiency virus (HIV) can be vertically transmitted from a woman living with HIV to her child during pregnancy, childbirth, and breastfeeding. Antiretroviral therapy (ART) prevents vertical transmission of HIV by providing prophylaxis to the fetus or infant and lowering the …
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Adverse impact of hospitalisation on infant breastfeeding practices: a prospective cohort study
… 119 mothers (median age 26 years, IQR 22-32; 28% HIV-positive) were interviewed at admission; 39% (46/119) breastfed exclusively (EBF) and 28 (24%) reported no breastfeeding. Most infants (median age 1.8 months, IQR 1.0-3.2; 34% preterm) were admitted for lower respiratory tract infection (59%) or …
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HIV-related knowledge and antiretroviral therapy outcomes (ART) in HIV infected women initiating ART during pregnancy
The characteristics of South Africa’s HIV epidemic mean that approximately 28% of women presenting for antenatal care, are HIV-infected. Maternal HIV-infection can lead to mother-to-child transmission (MTCT) of HIV during pregnancy, labour, delivery or breastfeeding if viral load (VL) is not well …
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The effect of HIV status on perinatal outcome at Mowbray Maternity Hospital and referring MOUs
… sub-Saharan Africa the most affected region. Maternal HIV infection is the leading cause of maternal and child morbidity and mortality in South Africa. A meta-analysis of world literature suggests a clear association between HIV infection and perinatal mortality. Aims and Objectives: To study …
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Factors associated with Nevirapine adherence in the prevention of mother-to-child transmission of HIV in the Free State province of South Africa and discrepancies between service records and cord-blood surveillance
Sub-Saharan Africa holds 90% of the HIV-infected children worldwide and most of them are infected through vertical transmission. The elimination of mother-to-child transmission of HIV in this region can be achieved through complementing prophylaxis regimens with effective service delivery. The …
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Growth, infectious morbidity, and neurodevelopment of HIV-exposed and HIV-unexposed infants in the context of lifelong maternal antiretroviral therapy and breastfeeding: a prospective cohort study
Background In 2019, 1 million in utero-HIV-exposed but -uninfected children (CHEU) were born in sub-Saharan Africa. In the absence of breastfeeding and maternal antiretroviral therapy (ART), HIV-exposed uninfected children (CHEU) have higher risks of mortality, growth faltering, infectious …
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Regional neurometabolite trajectories and how they relate to neurocognitive
… brain health and function are built, exposure to maternal HIV and/or antiretroviral therapy (ART) during in utero and/or early postnatal development may adversely affect functional brain development and subsequent neurological functioning, in children who are exposed to HIV and/or ART perinatally. …
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Caregiver, child and family characteristics associated with parenting stress in rural KwazuluNatal
… to increase risk of PS: the mother becoming HIV infected post-pregnancy, the family experiencing recent food insecurity, the child exhibiting internalizing or externalizing behaviours and the child having academic or other problems at school. Two factors were linked to a reduced likelihood of …
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