Global ETD Search
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Showing 1 to 3 of 3 for “"Matα"”.
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Structural characterization of the MATα prepro-peptide secretion leader in Pichia pastoris
… secretion signal leader in P. pastoris is the MATα prepro signal leader, originally found in S. cerevisiae. However, because some proteins cannot be secreted efficiently by P. pastoris, strategies to enhance secretion efficiency have involved the modification of the MATα prepro secretion signal …
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The effects of cis- and trans-acting mutations on recombinant protein secretion in Pichia pastoris
… Multiple tools such as the cis -acting factors MATα secretion signal and MBP fusion partners, and trans-acting modifications such as the bgs mutants have increased heterologous protein secretion. Although these techniques have already been used, their effects on the protein secretory pathway …
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Characterization of the MATα pre-/pro- peptide by mutagenesis as a means to optimize secretion in pichia pistoris
<p>The unicellular yeast, <em>Pichia pastoris</em> has currently emerged as one of the most popular host systems for heterologous proteins due to its relatively cheap cost, easy genetic manipulability, ability to perform post-translational modifications on proteins, and respiratory growth …