Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Mass drug administration"”.
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The potential health impact of ivermectin mass drug administration for malaria control on swine in Mozambique
… trial assessing the use of ivermectin (IVM) mass drug administration to humans and pigs for the control of malaria vectors in the Mopeia district in Mozambique, a longitudinal study to assess the impact of IVM administration on pig health was performed. METHODS: Beginning in March 2022, IVM …
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Environmental Fate of Ivermectin and its biological metabolites in Soils: Potential implications for the Environmental Impact of Ivermectin Mass Drug Administration for Malaria Control
… data suggests that most IVM-administered drugs remain intact, and more than 90 % of this drug is eliminated in feces. Biological metabolites: 3′′-O-demethylivermectin (3DI) and 24-hydroxymethyl ivermectin (24OHI) are also excreted in feces. Therefore, using manure from treated cattle as …
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Comparative and population genomic analyses of the parasitic blood flukes
… for control and ultimately elimination through mass-drug administration (MDA), reliant on the only available drug, praziquantel. In this thesis, I first present the results of the first genomic study investigating the potential impact of long-term mass-drug administration (MDA) on Schistosoma …
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A mathematical modelling approach for the elimination of malaria in Mpumalanga, South Africa
… Interventions such as scaling-up vector control, mass drug administration, focal screen and treat campaign at the Mpumalanga-Maputo border-control point and source reduction are applied to the model to assess their potential impact on transmission and whether they may be used alone or in …
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The Impact of Ivermectin Treatment in Cattle on Dung Degradation and Fauna Abundance and Diversity in Tanzania
Ivermectin also called the wonder drug has been used over the years to control internal and external parasites in livestock. In humans it has been used for the control of several neglected tropical diseases. With regards to efforts to control malaria, mass drug administration (MDA) of ivermectin in …
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An investigation of challenges that impede the elimination of malaria in Andara district, Kavango east region, Namibia
… should implement different interventions such as mass drug administration, mass testing and treatment and mass relapse prevention in order to reduce malaria transmission. The government should also implement targeted testing and treatment, routine testing and treatment at points of entry and …
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Biophysical characterisation of the interaction between the S.mansoni G4LZI3 protein and the NAD binding domain of glyceraldehyde-3 phosphate dehydrogenase
… control of the schistosomiasis morbidity through mass drug administration of Praziquantel (PZQ) to school-aged children and other high risk individuals. Although, the extensive use of PZQ as the main drug readily available for large scale treatment of schistosomiasis in most of African regions has …
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Impact of the parasitic helminth Schistosoma mansoni on host anti-viral vaccine responses: proof of concept from the anti-polio vaccine
… When attempting to control the disease by administration of the sole commercially available drug for schistosomiasis control, praziquantel, the parasite-driven depletion of the plasma cell and memory T cell compartment was restored followed by a partial recovery of antibody-producing …
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Soil-Transmitted Helminths Surveillance in Benin: A Mixed-Methods Analysis of Factors influencing Participation in Longitudinal STH Surveillance Activities
… to deworming, including community-wide mass drug administration (MDA). Transitioning from a policy of STH control to transmission interruption will require rethinking existing STH surveillance protocols. Surveillance will be crucial for identifying priority areas for community-wide MDA, …