Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Maspin"”.
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The Tumor-Suppressive Role Of Secreted Maspin Via The Exosomes
… dissertation highlights several novel findings. Maspin has been consistently detected in the conditioned media of maspin-expressing cells of normal and tumor breast, prostate and lung origin. Furthermore, extracellular maspin has been demonstrated to have anti-tumor effects. Interestingly, maspin …
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Epigenetic silencing of BRCA1 and maspin in sporadic breast cancer
… of the tumor suppressor genes BRCA1 and maspin are frequently decreased or lost in sporadic breast cancer. We hypothesized that inactivation of these genes was due to aberrant epigenetic silencing at the level of gene transcription. In this study we show that aberrant cytosine methylation …
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RESVERATROL INHIBITS PROSTATE CANCER GROWTH AND METASTASIS BY TARGETING AKT/MICRORNA-21 PATHWAY
… namely programmed cell death 4 (PDCD4) and maspin. Thus, drugs which target <italic>miR-21</italic> for inhibition could provide novel treatment options for metastatic prostate cancer. Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin found in high quantities in various …
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Charakterisierung von Leupaxin und seiner Interaktionspartner in Karzinomzellen
… Kinase JNK zu. Die TAK1-JNK-ATF-2-Zielgene Maspin und Presenilin1 zeigen in PCa-Zellen mit herunterregulierter LPXN-Expression eine signifikant herunterregulierte Expression. LPXN interagiert mit dem Aktin bindenden Protein Caldesmon. In PC-3-Zellen lokalisiert Caldesmon an den …