Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"Marine sponges"”.
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The Contractile System of Marine Sponges
Made available in DSpace on 2014-12-09T23:33:51Z (GMT). No. of bitstreams: 1 6503171.pdf: 7505298 bytes, checksum: b7d6a032b3d09976f65ebf1c6823a702 (MD5) Previous issue date: 1964
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Microbiology of marine sponges: from community structure to symbiont function
Marine sponges are filter-feeding metazoans that can host complex microbial communities which comprise as much as 35% of total sponge biomass. In this thesis I have employed high-throughput, next-generation sequencing technologies to study the sponge microbiota at two different scales. Firstly, I …
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Antiviral, Cytotoxic and Antimicrobial Compounds From Marine Sponges and Algae (Biological Activity)
The antiviral and antimicrobial compounds sceptrin, oxysceptrin, bromosceptrin, debromosceptrin, dibromosceptrin and debromooxysceptrin have been isolated from the sponge Agelas mauritiana and their structures have been determined by spectroscopic means. Syntheses of model compounds for some of the …
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Chemical studies of metabolites from Pacific Ocean marine sponges and the starfish Dermasterias imbricata
… active extracts of several Pacific Ocean marine sponges has led to the isolation of eight new and nine previously known natural products. The structures of the compounds were determined by a combination of spectroscopic data analysis and chemical interconversions. In addition, the partial …
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Isolation and structure elucidation of bioactive secondary metabolites from marine sponges and sponge-derived fungi
… products from bacteria, fungi, plants and marine organisms exhibit unique structural diversity which are of interest for the identification of new lead structures for medicinals and agrochemicals. In the search for bioactive compounds from marine sponges and sponge-associated fungi, this …
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The biogeography and trophic roles of coastal marine sponges (Porifera) from the west coast of the North Island, New Zealand: Influences of catchments.
Anthropogenic activities are degrading coastal marine ecosystems globally. While the ecological and biodiversity implications of some of these impacts are well understood, for others there is a need for a greater understanding of the effects of these activities on vulnerable sedentary species. For …
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Metabolomics as a tool in the identification and production of new marine-derived antibiotics from sponges and endosymbiotic bacteria
… antibiotics and pharmacologically-active drugs. Marine sponges and their endosymbionts have proven to be abundant sources of bioactive compounds. HR-LCFTMS and NMR were used in the identification of compounds isolated from a marine bacterium and its host sponge, as well as in the dereplication …
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Distinção de espécies de Amphimedon Duchassaing & Michelotti, 1864 (Niphatidae, Haplosclerida, Demospongiae) da costa brasileira por estudos de diversidade genética e morfológica
… of this method for the distinction of species of marine sponges.
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Synthesis Of Natural Product-Based Sphingosine Derivatives
Marine sponges represent an excellent source of sphingolipids and their metabolites, especially sphingosine-1-phosphate (S1P). S1P plays an important role in cell differentiation, survival, proliferation and the immune response. The enzyme sphingosine kinase (SK) is critical for the phosphorylation …
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Bromotyrosine-derived natural products: synthetic and biological studies
… class of compounds that are produced by marine sponges of the order Verongida. Furthermore, they exhibit a rich variety of chemical structures and display a diverse range of bioactivities which makes them of great interest to both the chemical and biological research communities. This …
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Antimicrobial activities and diversity of sponge derived microbes
In this study, marine sponges collected in Irish waters were analysed for their associated microbiota. Of the approximately 240 bacterial isolates obtained from two sponges several showed antimicrobial activity; among them members of genera which have rarely been shown to produce antimicrobial …
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The Use of C. Elegans to Identify Mutations That Confer Drug Resistance, Using Hemiasterlin as an Example
… product isolated from the several species of marine sponges. Hemiasterlin inhibits microtubule polymerization resulting in cell cycle arrest and apoptosis. Cells over-expressing efflux pumps associated with multidrug resistance are not resistant to the toxic effects of hemiasterlin. Because of …
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Synthetic efforts toward the eastern hemisphere of theonellamide C
… A-F are bicyclic dodecapeptides isolated from marine sponges of the genus Theonella and were shown to display potent antifungal activity. Despite considerable synthetic effort to produce TNM F by the Shioiri group in the early 1990s, a total synthesis of a TNM has yet to be reported. This …
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Total synthesis of marine terpenoids
Complex architectures of marine terpenoids and vast assortments of their scaffolds have served as a proving ground for synthetic chemists, inspiring them to develop, assess, and test new methodologies and disconnections. Moreover, besides advancing the field of organic synthesis, marine natural …
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Functional Studies of Novel Bioactives From Complex Host-Microbiomes as Drug Leads for Cancer, Infectious Disease, Depression and Pain
… calcium channel blocker Prialt (ziconotide), marine natural products has been validated as a source for new medicines. However, the demand for natural products is extremely high due to the development of high-throughput assays and this bottleneck has created the need for an intense focus on …
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Genomics approaches to exploit the biotechnological potential of marine sponge-derived Streptomyces spp. isolates
… diverse environmental niches, such as marine ecosystems, mangroves, and symbiotic communities of insects and sponges, resulting in the discovery of a variety of previously unidentified compounds of pharmacological interest; including those isolated from marine-derived Streptomyces …
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Marine bacteria as a source of polyester-degrading enzymes with biocatalytic potential
… few PET-hydrolyzing enzymes were reported from marine environments, an aspect which we hoped to expand upon. In chapter 2, activity screening and genome mining of marine bacterial isolates led to the identification of a polyesterase, BgP, from a deep-sea, marine sponge-derived Brachybacterium …
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Synthesis of chiral intermediates by deritivization of monosaccharides
… peptide serine protease inhibitors isolated from marine sponges and cyanobacterial water blooms. Rigid bicyclic amino acid(Choi)is an essential core structure, which strongly influences biological activity of aeruginosin family members. Aeruginosins showed promising inhibitory activity against …