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Showing 1 to 1 of 1 for “"Mapping stringency"”.
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A Quantitative Exploration of Causes of False Positive Single Nucleotide Polymorphisms in Next-Generation Sequencing Data
… approach to SNP discovery is based on mapping reads to a reference sequence. Apart from sequencing errors, which vary in pattern and rate depending on the sequencing platform, the short read lengths that prevail in NGS, together with the repetitive nature of the genomes of many …