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Showing 1 to 20 of 183 for “"Mannose"”.
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UNVEILING THE ROLE OF THE MANNOSE RECEPTOR IN CARDIOMETABOLIC DISEASES
OBIETTIVO: Le malattie cardiometaboliche sono caratterizzate da uno stato di infiammazione sistemica che contribuisce attivamente alla patogenesi, per cui lo studio di modulatori dell'attivazione immunitaria potrebbe offrire nuovi bersagli terapeutici. Il recettore del mannosio (Mrc1) è un …
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Regulation of the Mannose PTS Operon by the small RNA SgrS
… that SgrS regulates the genes encoding the mannose and secondary glucose transporter, manXYZ. Analysis of manXYZ mRNA stability and translation in the presence and absence of SgrS indicate that manXYZ is regulated by SgrS under stress conditions and when SgrS is ectopically expressed. In …
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Untersuchungen von Mikroglia-Zellen und des Mannose-Rezeptors unter einem immunologischen Blickwinkel
Die Rolle des Mannose-Rezeptors in Mikroglia-Zellen wurde untersucht. Durch Stimulation mit Cytokinen wurde die Regulation der Expression und Aktivität des Mannose-Rezeptors in einem immunologischen Umfeld in Mikroglia-Zellen simuliert. Die erhaltenen Ergebnissse sprechen für eine Beteiligung des …
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Wechselwirkungen von Proteinen mit den zytoplasmatischen Domänen der Mannose-6-Phosphat-Rezeptoren
… die mit der zytoplasmatischen Domäne des 300 kDa Mannose-6-Phosphat-Rezeptors (MPR300-CT) interagieren. Für die Wechselwirkung zwischen Periplakin und dem MPR300-CT sind die N-terminalen 29 Aminosäuren der Rezeptordomäne, die das Tyrosin-haltige Internalisierungssignal umfassen, ausreichend und …
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A Synthesis and Characterization of D-Lyxo-Hexos-5-Ulose From D-Mannose.
A convenient synthesis of 5-keto-mannose (D-lyxo-hexos-5-ulose, 20) from D-mannose is described. Methyl 2,3-0-isopropylidene-a-D-manno furanoside was converted to its crystalline 6-0-triphenylmethyl ether which in turn was oxidized at the C-5 hydroxyl group with either methylsulfoxide/acetic …
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Acanthamoeba spp. Secrete a Mannose-Induced Protein that Correlates with Ability to Cause Acanthamoeba Keratitis
… keratitis begins when Acanthamoebae bind to mannose expressed on traumatized corneas. Published reports indicate that mannose is upregulated on the corneal surface during wound healing. Experiments in laboratory animals have shown that corneal abrasion prior to infection is essential for …
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Functional Significance of Glycoprotein Clearance by the Asialoglycoprotein Receptor and the Mannose/GalNAc-4-SO4 Receptor
… ones bearing terminal Gal/ GalNAc and that the Mannose/GalNAc-4-SO4 receptor: MR) is capable of clearing glycoproteins bearing terminal GalNAc-4-SO4. I am taking a genetic approach identifying endogenous ligands for the ASGR and the MR in vivo and establishing the biologic significance of …
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Mannose and Lipopolysaccharide Receptors on the Surface of Granular Hemocytes from the Crayfish <em>Procambarus clarkii</em>.
… have been shown to bind to both LPS and a mannose containing neoglycoprotein conjugated to fluorescent probes. A decrease in the observed number of fluorescent hemocytes indirectly indicated that the binding of FITC-LPS to these cells is impaired by initial incubation with LPS. Prior …
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The influence of monosaccharide types (D-glucose, D-mannose and D- galactose) in inducing lactic acidosis in goats
Call number: LD2668 .T4 1978 M78
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Solution-phase and automated solid-phase synthesis of high-mannose oligosaccharides : application to carbohydrate microarrays and biological studies
(cont.) 2G12, cyanovirin-N, and a recently identified anti-HIV protein, scytovirin.
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Investigating the effect of prophylactic D-mannose treatment on adhesion of Uropathogenic Escherichia coli to the human bladder epithelium
… Several studies have suggested that D-mannose reduces the binding of UPEC to the lining of the bladder in vitro and in animal models. This study used a 3D bladder epithelial cell model to investigate UPEC binding in the presence of urine samples from the women enrolled on a double-blind …
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Biochemical characterization of five GH130-family enzymes from Caldanaerobius polysaccharolyticus ATCC BAA-17 and insights on their metabolic role and reaction mechanisms
… of β-1,2 and β-1,4-mannosyl linkages between the mannose at the non-reducing end of substrates and mannose, glucose or N-acetylglucosamine residues, with the subsequent release of α-mannose-1-phosphate. In this study, we compare five different GH130 enzymes (CpMan130 A-E) encoded within the genome …
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Complexity of the Late Stages of GPI Anchor Biosynthesis in Saccharomyces Cerevisiae
… of adding phosphoethanolamine to the third mannose of the mammalian GPI anchor. Genetic disruption of the yeast PIG-F gene (termed GPI11), demonstrated that it is essential for vegetative growth. Yeast gpi11 mutants in which the Gpi11 protein (Gpi11p) could be conditionally depleted were …
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Glycan polymeric prodrugs against pulmonary intracellular alveolar infections
… active drug. We hypothesized that engineering mannose glycopolymer prodrugs to target the macrophage mannose receptor on alveolar macrophage cells would eradicate or minimize bacterial replication and allow for better protection against intracellular infections. We demonstrated that mannose …
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Structural and compositional studies of potential immunomodulatory polysaccharides found in locally grown plants
… contains acemannan, a highly water-soluble mannose rich glucomannan, which has demonstrated immunogenic responses in humans and animals. Aloe ferox, a locally grown species, is commercially marketed as an equivalent to Aloe vera and is being substituted in various health products. This …
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Purification and identification of sulfated Lewis X binding proteins in boar sperm
… studies have proposed that glycans containing mannose termini are the structures recognized by the sperm protein AQN1. However, using a novel screening approach, our group has established that pig sperm bind preferentially to glycans containing the Lewis X trisaccharide (LeX) or multi-antennary …
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Biochemical characterization of Cj 1123 c, a putative acetyltransferase & Cj 1319, a putative C6 dehydratase from Campylobacter jejuni.
… acetyltransferase and Cj 1319, a putative GDP-mannose dehydratase encoded by the N- and O-linked protein glycosylation loci in C. jejuni, respectively. We show that Cjll23c is responsible for the synthesis of UDP- diacetamidobacillosamine. We also show that Cj 1123c can N-acetylate the O- …
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Bioconversion of lignocellulosic hydrolysate to acetic acid using Moorella thermoacetica
… can partially consume arabinose, galactose and mannose within 72 h of fermentation. Acetic acid yield in forest residues was adversely affected by high concentration of arabinose, galactose and mannose. Glucose to xylose ratio has a direct effect on production yield. It was also observed that M. …
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