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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 117 for “"Mannitol"”.
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Physiological and ecological studies of mannitol utilizing marine bacteria
Bacteria were isolated from the kelp beds on the West Coast of South Africa. Strains isolated from the water column and kelp fronds were classified as Pseudomonas, Vibrio, Acinetobacter and Flavobacterium species. Bacterial diversity in adjacent kelp dominated habitats was examined using numerical …
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Aromatic alcohol oxidase, aldehyde oxidase and mannitol oxidase in terrestrial gastropods
… of the A. ater and L. flavus activities. D-Mannitol oxidase thus far has only been reported in gastropod molluscs. Activity from the four species mentioned above is very similar with regard to substrate preference and apparent Km values. o-Mannitol, D-arabitol and to a lesser extent sorbitol …
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Expression, sequencing, and characterization of mannitol-1- phosphate dehydrogenase genes from Aspergillus parasiticus and Escherichia coli
The genes coding for mannitol-1-phosphate dehydrogenases (mtlD) from Aspergillus parasiticus and Eschericia coli were cloned and sequenced. The two coding regions were highly homologous and the identity was 88.7% at the amino acid level and 81.6% at the nucleotide level. The two genes translate …
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Sugar-Derived Oleogels in Cosmetics and Food Applications: a Case Study of Trehalose- and Mannitol-Based Gelators
… skin protectant and moisturizer, while mannitol has found extensive applications in food industry. <em>We hereby present an environmentally-friendly synthetic procedure of trehalose- and mannitol-based derivatives, their characterization, gelation ability and surface activity. In this …
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Allergen-induced change in airway responsiveness to direct and indirect stimuli in mild atopic asthmatics
Methacholine (MCh) and mannitol challenges are tests used to assess airway responsiveness. It has been shown that airway responsiveness to direct bronchoconstrictors like MCh tends to increase following exposure to allergen but the response to mannitol an indirect stimuli, is not known. …
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SPRAY-DRIED BIOADHESIVE FORMULATIONS FOR PULMONARY DELIVERY
… in the residence time of drug in the lung. Mannitol or lactose monohydrate (LMH) aqueous solutions were spray dried at inlet temperatures of 90, 130, 170 or 210ºC. Soy phosphatidylcholine and cholestrol (1:1 mole ratio) were used in all formulations. Cholesterol was added to increase vesicle …
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Analysis of the Structural Units of Sulfated Glycosaminoglycans by High Performance Ion Exchange Chromatography
… acid)-6-O-sulfo-2,5-anhydro-D-mannitol (GMS), two-L-iduronic acid-containing monosulfated disaccharides, 4-O-((alpha)-L-idopyranosyluronic acid)-6-O-sulfo-2,5-anhydro-D-mannitol (IMS) and 4-O-(2-O-sulfo-(alpha)-L-idopyranosyluronic acid)-2,5-anhydro-D-mannitol (ISM), and a …
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Investigation to Identify the Influence of Mannitol as a Carrier on the Ex-Vivo Dose Emission and the In-Vitro Aerodynamic Dose Emission Characteristics of Dry Powder Inhalers of Budesonide
… of budesonide with crystallised β-form mannitol, commercial DPI grade mannitol and lactose. The lactose-budesonide was the marketed Easyhaler® 200 g formulation. Ex vivo assessment of deposition using the Easyhaler® multi-dose high resistance inhaler with reservoir was compared with the …
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Modification of natural hydrophilic polymers for use in pharmaceutical formulations
… prepared from commercially available crystalline mannitol and -chitin using direct compression as well as spray, wet and dry granulation. The effect of the ratio of the two components, percentage of lubricant and particle size on the properties of the prepared co-processed excipient has been …
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Identification and characterisation of lactic acid bacterial secondary metabolites with functional and health benefits
… for identification of EPS producing isolates. Mannitol is a six-carbon polyol that is 50-70% as sweet as sucrose but with only half the calories. With the rising demand for low calorific dairy products there is a need for alternative sweetening methods. In Chapter Four we included a mannitol …
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Intracranial hypertension in Kenyan children with cerebral malaria
… a poor outcome despite aggressive therapy with mannitol. One child with a maximum ICP of 151 mmHg died with the signs of uncal and medullary stages of herniation. In the other 2 children, middle cerebral artery velocity and vascular resistance monitored with TCD sonography changed with ICP and …
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Mechanistic Insights into the Stabilisation of Biopharmaceuticals using Glycine Derivatives. The Effect of Glycine Derivatives on the Crystallisation, Physical Properties and Behaviour of Commonly used Excipients to Stabilise Antigens, Adjuvants and Proteins in the Solid State
… derivatives on the solid state properties of mannitol, glycine, and sucrose when freeze dried into blended mixtures. The primary goal was to assess their value for use in the stabilisation of vaccines in the solid state, by examining key physical and chemical characteristics, which have been …
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A Model for Studying Vasogenic Brain Edema
… brain using multiple infusions of hyperosmotic mannitol (0.25mL/kg/s over 30 seconds) delivered through the right internal carotid artery. Magnetic resonance imaging (MRI) revealed consistent edema formation and high water levels in the ipsilateral gray and white matter within an hour of the …
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FUNCTIONAL ADAPTATION OF THE RUMINAL EPITHELIUM
… mL) flux, and serosal to mucosal flux of 3H-mannitol (JSM-mannitol; 74 KBq/15 mL) and tissue conductance were measured. Half of the chambers assigned to measure JMS-acetate and JMS-butyrate were further assigned to 1 of 2 acetate and butyrate concentration treatments: 10 mM (Low) and 50 mM …
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Occurrence and Growth Characteristics of Algae Isolated From Shallow Wells, Deep Wells, and Springs in Northwest Arkansas and Southwest Missouri
… strains were cultured in media supplemented with mannitol, glucose, fructose, and sucrose to see which substrate or substrates best supported heterotrophic growth of the algae. Of the substrates tested, glucose and fructose supported growth in the dark most readily, and mannitol was found to be …
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Nanotechnology in pulmonary drug delivery: Compressible proliposome formulations for nebulization
… monohydrate (LMH), sucrose, sorbitol and D-mannitol), in three formulation ratios (i.e. 1:5, 1:10 and 1:15 w/w lipid to carrier) for the preparation of proliposome powders and tablets. Two dispersion media; deionised water (DW) or deuterium oxide (D2O) were used to generate liposomes from …
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Bioethanol Production from Macroalgae
… on the storage carbohydrates laminarin and mannitol and the structural carbohydrates alginate, cellulose, fucoidan and xylose. In addition to carbohydrates the protein, nitrogen, carbon, polyphenol, ash and metal content was also profiled. Chemical profiling identified all four kelps as …
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Quantifying Renal Swelling during Machine Perfusion using Digital Image Correlation
… solution (PBS) and PBS supplemented with 5% w/v mannitol were used as isotonic (289 mOsm/kg) and hypertonic (568 mOsm/kg) perfusates, respectively. Porcine kidney pairs were procured then flushed and machine perfused; the right and left kidneys were assigned opposite perfusates. An experimental …
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Characterization and Genetic Analysis of The Morphological Mutant <em>Crisp-5</em> of <em>Neurospora crassa</em>
… sucrose, 2% glucose, 2% fructose, 2% lactose, 2% mannitol. 2% glycerol, 2% sorbitol or 2% sorbose. The <em>cr-5</em> mutant grew better on glucose and fructose separately than it did on sucrose. Both the mutant and wild type grew very poorly on lactose, mannitol, sorbitol and glycerol. The pattern …
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