Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"Mammary glands"”.
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Intramammary infection in rapidly growing, non-lactating mammary glands
Intramammary infections (IMI) are common in non-lactating heifer and dry cow mammary glands and occur during periods of appreciable mammary growth and development. The presence of these infections is expected to negatively impact mammary growth and development but has yet to be investigated. The …
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The influence of hormones on fetal mouse mammary glands in vitro
Thesis (M.S.)--Michigan State University. Dept. of Zoology, 1972
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Overexpression of ovine insulin-like growth factor-I (IGF-I) in the mammary glands of transgenic mice
Evidence indicates that the mammary gland may contribute to its own development by the production of insulin-like growth factor-I (IGF-I). To generate a model for investigation of the effects of enhanced IGF-I synthesis in the mammary gland, six transgenic founder mice were produced by …
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The Roles of Relaxin, Estrogen and Progesterone on Growth and Remodeling of the Cervix and Mammary Glands in the Gilt
We recently described relaxin-induced changes in physical and biochemical properties of the cervix that occur during the last third of the 115-day gestation period in the gilt. Histological changes in the cervix that occur between days 80 and 110 of pregnancy and the effects of relaxin on those …
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The effects of dietary lipids on the fatty acid composition of tissue and membrane fractions of spontaneous mammary adenocarcinomas and mammary glands of Strong strain A mice
… of whole tissue and plasma membrane fractions of mammary adenocarcinomas and normal mammary glands excised from Strong A female mice fed a 15% safflower oil and 15% tallow diets were studied. Previous work has indicated that high fat diets in general and high unsaturated fat diets in particular, …
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Xenogeneic transplantation of immortalized bovine mammary epithelial cells
… to investigate the use of an immortalized bovine mammary epithelial cell line as a starting material for xenogeneic transplantation into the mammary glands of immunocompetent recipients. PSG-5 cells (a clonal derivative of the MAC-T cell line engineered to express ovine IGF-I ) were transplanted …
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The effects of dietary protein intake by the dam and by the offspring on mammary gland development in young female rats
… of dietary protein (casein) at different ages on mammary gland development in first generation female Sprague Dawley rats. Offspring were fed the same diet as fed to their dams during gestation and lactation, or offspring were crossed over at weaning to different protein intakes, from control dams …
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The Role of Insulin-like Growth Factor-I and IGF-binding Proteins in Mammary Gland Development
Development of the mammary gland is likely mediated by locally produced growth factors acting in concert with circulating mitogens. To investigate the importance of mammary synthesis of insulin-like growth factor-I (IGF-I) and IGF-binding proteins (IGFBP), the initial objective was to evaluate the …
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Effects of feeding level and diet composition on mammary growth in prepubertal lambs and mice
… libitum fed groups. Lambs in group S had heavier mammary glands, with greater amounts of parenchyma and fat pad and higher content of dry, fat-free parenchymal tissue compared to the mean of the remaining groups. Total gland weight was lower in group R, although weight of parenchyma was similar to …
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A Proteomic Analysis of Differentiation in the Mammary Epithelium
… and the structural development of the mammary gland from pregnancy to lactation, very little is known about the molecular mechanisms governing differentiation of the mammary epithelium into a milk-secreting phenotype. It is important to acknowledge the diversity among the mammary glands …
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The role of Wnt signalling during embryonic salivary gland development
… that is a characteristic of the salivary glands and other organs including the lungs, kidneys and mammary glands. Branching morphogenesis is the mechanism by which a single epithelial bud undergoes repetitive cycles of bifurcation in order to maximise its surface area within a confined …
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Efficacy of tamoxifen and thymoquinone on tumor development, lipid peroxidation, and total antioxidant capacity in DMBA induced mammary carcinoma in female Sprague-Dawley rats
… (control, DMBA, TAM, TQ, and TAM+TQ) were used. Mammary tumors were induced by DMBA which was given by oral gavage to four groups: DMBA, DMBA+ TAM, DMBA+ TQ, and DMBA+ TAM & TQ. The control group received tap water only. Starting three weeks later, TAM and/or TQ were administered daily for 10 …
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Modeling Brk/PTK6 expression in the mammary epithelium.
… and intestine, Brk is notably absent from normal mammary tissue and non-transformed mammary epithelial cell lines. The role of Brk/PTK6 in breast pathology is unclear. We hypothesized that Brk expression in non-transformed mammary epithelium would promote tumorigenesis. To determine the effects …
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Predicting post-absorptive amino acid supply to the mammary tissue
… current models. A greater supply of AA to the mammary glands does not always mirror AA absorption—the process by which absorbed AA convert into milk protein is variable, and this may be linked to the way the udder regulates AA uptake to preserve intracellular balance. AA transporters housed …
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Ability of Klebsiella spp. mastitis isolates to produce virulence factors for enhanced evasion of bovine innate immune defenses
… factors enabling Klebsiella spp. survival in the mammary glands of multiple animals may provide insight into host adaptation. In this study, Klebsiella spp. strains were evaluated for their ability to evade neutrophil killing, the primary immune defense in the bovine mammary gland. Our research …
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Role of Cuzd1 in mammary gland development and tumorigenesis
… the epidermal growth factor (EGF) family control mammary development are unclear. We have identified the CUB and zona pellucida-like domain containing protein-1 (CUZD1) as a target of estrogen regulation in the mouse mammary epithelium. Mice lacking Cuzd1 exhibited a striking impairment in …
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Thymoquinone decreases oxidative DNA damage (8-OHdG) in DMBA treated female Sprague Dawley rats
… (a)anthracene (DMBA, a drug that induces mammary cancer). 8-OHdG is the most commonly assayed fingerprint of free radical attack on DNA and is involved in tumor progression. Five groups of 10 rats (Controls, DMBA, TAM, TQ, and TAM+TQ) were treated for 10 weeks after injection of DMBA. …
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The effect of maternal nutrition on offspring gene regulation via epigenetic modulation
… been shown to affect tumor suppressor loci in mammary gland cancer cells. However, it is not known how these tumor-suppressive genes are regulated by epigenetic changes in the mammary glands in vivo under maternal low-protein (LP) diet. One of my published projects examined the effect of …
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Assessing Availability and Utilization of Essential Amino Acids in Dairy Cattle Using Stable Isotope Based Approach
… and to evaluate the metabolism of amino acids in mammary glands of dairy cattle using stable isotope-based approaches. In the first experiment, seven heifers (258 ± 28 kg BW) were randomly chosen and assigned to 8 treatment sequences in a 7 x 8, incomplete, Latin square design. Treatments were a …
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