Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Mammals--Genetics."”.
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Adenovirus-based exogenous gene expression in mammalian cells
Adenoviruses have been used as a model system for understanding gene expression, DNA replication, gene delivery and other molecular biological phenomenon. In this project, adenovirus was used as a model to study exogenous gene expression in mammalian cells. More specifically, several adenoviral …
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Characterization of ARV1-Mediated Sterol Transport in Yeast and Mammalian Systems
Saccharomyces cerevisiae Arv1p (𝘈𝘙𝘌2 required for viability 1) is an endoplasmic reticulum (ER)-localized, functionally conserved protein that was initially observed to mediate subcellular sterol distribution, and has since been implicated in the movement of multiple lipid species. In this thesis, …
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Studies on mammalian pre-mRNA splicing : connections to transcription and cancer
This thesis presents two separate pieces of work pertaining to pre-mRNA splicing in mammalian cells. The first part examines the regulation of the alternative splicing of the PKM gene in cancer cells, while the second part investigates the physical connections between the transcriptional apparatus …
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Regulation of alternative splicing and its connections to cancer
This thesis presents two separate pieces of work pertaining to pre-mRNA splicing in mammalian cells. The first piece, as the main research project of the thesis, consists of two related parts. The first part identified the regulators of the alternative splicing of the PKM gene in cancer cells while …