Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Mammalian embryos"”.
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Maintaining Proper Levels of DNA Methylation Marks Through the TET Family is Critical for Normal Embryo Development in Pigs
… transcriptional regulation. After fertilization, mammalian embryos undergo dynamic changes in genome-wide DNA methylation patterns and the changes are essential for normal embryo development. Ten-eleven translocation (TET) methylcytosine dioxygenases are implicated in DNA demethylation by …
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Zebrafish Cardiac Development Requires a Conserved Secondary Heart Field
… is a conserved developmental domain in avian and mammalian embryos that contributes myocardium and smooth muscle to the cardiac arterial pole. This field is part of the overall heart field, and its myocardial component has been fate mapped from the mesoderm to the heart in both mammals and birds. …
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Modelling metabolic landscapes in human naive and primed embryonic stem cells
Early mammalian embryos undergo remarkable changes in their metabolism, with a global transition from oxidative phosphorylation to glycolysis as they transit out of pluripotency and begin to make the first cell fate decisions in preparation for gastrulation. In humans this transition can be …
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Transcriptional Regulation of Neural Crest-Derived Pharyngeal Arch Artery Development
… and is required for growth and development of mammalian embryos. As the heart matures, formation of the outflow tract is vital to establish appropriate connections with the vasculature. This process requires contribution from specialized neural crest cells, which originate in the neural folds …
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Transcriptional Regulation of Neural Crest-Derived Pharyngeal Arch Artery Development
… and is required for growth and development of mammalian embryos. As the heart matures, formation of the outflow tract is vital to establish appropriate connections with the vasculature. This process requires contribution from specialized neural crest cells, which originate in the neural folds …
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Cell Death as a Morphogenetic Basis for Abnormal Development in Mutant-Bearing and Teratogen-Treated Embryos.
Cell death is known to be a widespread and essential event during the normal development of many tissues and organs (Glucksmann, 1965). Whole organs may degenerate during normal organogenesis. For example, massive necrosis is necessary for the proper formation of the excretory and urogenital duct …
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Date with Destiny: Genetic and Epigenetic Factors in Cell Fate Decisions in Populations of Multipotent Stem Cells
… found in the Caudal Lateral Epiblast (CLE) of mammalian embryos, which contributes to the spinal cord and paraxial mesoderm. The aim here was to derive NMPs in vitro which exhibit similar gene expression patterns and function like their mouse embryo counterpart and study their renewal and …
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Cell Fate Decisions in the Early Mammalian Embryo
… This is in contrast to commonly studied non-mammalian embryos in which pre-patterning of the embryo, driven by spatially localised factors, is a common feature. However, early blastomeres of mouse embryos have been reported to have distinct developmental fates, potential and heterogeneous …