Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Malpighian tubule"”.
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Drosophila as a model for the Anopheles Malpighian tubule
The insect Malpighian tubule is involved in osmoregulation, detoxification and immune function, physiological processes which are essential for insect development and survival. As the Malpighian tubules contain many ion channels and transporters, they could be an effective tissue for targeting with …
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Modulation of innate immunity by the cGMP signalling pathway in the drosophila malpighian tubule
… Imd immune pathway. To do this, the Drosophila Malpighian (renal) tubule was used as a model system. The Malpighian tubule is a very well characterised, extensively studied epithelial tissue and for a number of years has comprised the model system of choice with regards to the study of the …
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An electrophysiological study of ion transport across the isolated perfused malpighian tubule of Onymacris plana
… of the ionic and electrical gradients across the Malpighian tubules of Onymacris plana is fundamental to the understanding of the transport mechanisms of fluid across the basolateral and apical membranes. Until now no one has investigated the isolated perfused Malpighian tubule of Onymacris plana …
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Studies on diuresis in the New Zealand earwig, Anisolabis littorea (White)
… had undergone some degree of dehydration. A Malpighian tubule bioassay preparation enabled the physiological activity of extracts of the terminal abdominal ganglia and pharmacologically actives substances to be monitored. Results obtained suggest that substances are present in the terminal …
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Describing the Ionoregulatory Changes that Underlie Cold Acclimation in Drosophila Melanogaster
… cold-acclimated flies experienced increased Malpighian tubule fluid and K+ secretion and reduced rectal K+ reabsorption. These changes were independent of Na+/K+- or V-type H+-ATPases. These results suggest that modification of Malpighian tubule and gut mitigate cold-induced hyperkalemia. …
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Mechanisms Underlying Variation in Insect Chill Tolerance: The Role of Ion and Water Transport
… modifications by comparing the hindgut and Malpighian tubule transcriptomes of warm- and cold-acclimated individuals. Cold acclimation modified the expression of hindgut and Malpighian tubule ion transporters, and hindgut structural (cytoskeletal and cell junction) genes. Rectal …
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Manipulation of second messengers by ectopic expression of receptors in transgenic Drosophila
… AMP (cAMP) and calcium (Ca2+) in the renal (Malpighian) tubule of the genetic model organism, Drosophila melanogaster. The importance of the second messengers cGMP, cAMP and Ca2+ in control of fluid transport makes the Malpighian tubule an ideal testbed for such technology. The actions of …
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Genetic and cytological investigation of Nucleostemin-1 in Drosophila melanogaster
… examination of highly differentiated larval Malpighian tubule cells depleted for NS1 showed a loss of cytoplasmic ribosomes with a concomitant appearance of cytoplasmic pre-autophagosomes. We interpret the appearance of these structures as indicators of cell stress response.
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A P-glycoprotein-like mechanism in the nicotine-resistant insect, Manduca sexta.
… demonstrated positive immunolabelling of the Malpighian tubules of M. sexta and R. prolixus and at the blood-brain barrier of the central nervous systems of M. sexta and P. americana. To assess the extent of P-glycoprotein involvement at the blood-brain barrier of M. sexta, I took advantage of …
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Studies on the Structure and Pathogens of the Small Hive Beetle (Coleoptera: Nitidulidae)
<p>The small hive beetle (Aethina tumida, SHB) is an invasive pest of honey bee (Apis mellifera) colonies in the United States. The adult and larval beetles can ruin honey through fecal contamination and by vectoring a mutualistic yeast (Kodamaea ohmeri) that causes honey fermentation. These …
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The effect of mTOR inhibitor rapamycin on a dietary Drosophila melanogaster model of calcium oxalate nephrolithiasis
… on the area of calcium oxalate concretion in the Malpighian tubules of a Drosophila melanogaster fed a lithogenic diet containing 0.1% sodium oxalate.