Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1110 for “"Malignant"”.
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Benign, potentially malignant & malignant oral lesions; an analysis of oral and gut microbiota
… on histology; benign (B) (n=15), potentially malignant (PM) (n=8), and malignant (M) (n=7) oral lesions. Methods: Using shotgun metagenomic sequencing, we analysed the microbiota profiles to determine their potential as biomarkers for oral malignancy. We looked at alpha diversity, beta …
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Trim24 In Normal & Malignant Hematopoiesis
<p>Treatment for acute myeloid leukemia (AML) has changed little in the past four decades. For the majority of AML patients, current treatment options include chemotherapy and allogeneic stem cell transplants, which also involves high-dose chemotherapy or radiation treatment. These options have …
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Vascular remodelling in malignant hypertension
The incidence of malignant hypertension (MH) fails to decline. Improved anti¬ hypertensive agents have reduced mortality, but the economic burden remains high due to complications such as end stage renal failure. Since the condition is initially asymptomatic, little is known about early …
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Pax3 expression in cutaneous malignant melanoma
… of aberrant PAX3 re-expression in cutaneous malignant melanoma (CMM). The transcription, factor encoded by PAX is amongst the first expressed in the embryo, with a principal role in the development of the melanocytic lineage. We theorised that abnormal re-expression of PAX3, consistently …
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Malignant hyperthermia: the anaestesia induced disease
Contains fulltext : mmubn000001_02788046x.pdf (Publisher’s version ) (Open Access)
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Monocytic lysozyme levels in malignant disease
Thesis (M.S.)--Michigan State University. Dept. of Pathology,
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Invasion and Proliferation in Malignant Cells
Two key events in the oncogenic process of tumor cells are to acquire uncontrolled proliferation and invasive properties. This allows the tumor to grow and invade beyond the tissue from which the tumor cells originate. We here specifically studied p16 and ERK1/2 with special focus on and the …
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Malignant Glioma: Chemosensitivity testing and Biomarkers
… during the management of several types of malignant tumours in routine clinical practice. The present work attempts to transfer the use of these two concepts to the management of malignant gliomas. Chemosensitivity testing was performed on twelve primary malignant glioma cultures at passage …
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Malignant Neoplasia of the Extrahepatic Biliary Tract
University of Minnesota Masters thesis. April 1922. Major: Surgery. 1 computer file (PDF); 64 pages.
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Characterisation of cytokine secretion in malignant gliomas
Cytokines are proteins produced by cells of the immune system. The working hypothesis of the thesis is to show that the lymphocytes and glial cells in Glioblastoma Multiformae patients have an altered pattern of secretion of cytokines compared with low-grade and non-cancerous patients. Lymphocyte …
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A Translational Study Evaluating the Uses of Diagnostic and Therapeutic Practices Established in Human Malignant Melanoma in Equine Malignant Melanoma
Malignant melanoma is a neoplasm of melanocytes. It typically originates in skin, but may metastasize to other body systems. It is a relatively common neoplasm in both humans and horses, with striking similarities across both species. Heritable genetic factors associated with melanoma have been …
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Metformin as a potential therapy for malignant astrocytoma
Background Glioblastoma Multiforme (GBM) is the most commonly occurring tumour of the central nervous system (CNS). Currently GBM is considered an incurable malignancy with patients experiencing abysmal life expectancies. Lack of progress in the discovery of novel treatments has led to the …
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Stem cell based therapy of malignant brain tumors
Malignant brain tumor is a highly invasive and vascularized cancer. Current forms of therapy are not curative and can, at best, prolong survival for patients with this disease. The mean survival is only around 15 months. The aims of the present thesis have been to develop and explore a stem cell …
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Protein and uric acid patterns in malignant disease
… detailed study of 92 patients suffering from malignant disease and all receiving cytotoxic drugs,a number of interesting facts emerged.
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Targeting oncogenic microRNAs in malignant germ cell tumours.
Malignant germ cell tumours (mGCTs) are a heterogenous group of tumours that occur primarily in the testes and ovaries but also in other anatomical sites, and affect people of all ages. It was established by the Coleman group through microRNA profiling in 2010 that all mGCTs, regardless of tumour …
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