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Showing 1 to 3 of 3 for “"Male meiosis"”.
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Transcriptional and developmental consequences of aneuploidy during male meiosis
… genome integrity is especially important during meiosis, the specialised cell division programme in the germline that generates haploid gametes. As these cells transmit genetic information to the next generation, the consequences of meiotic errors are not restricted to an organismal level, but …
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Developmental transitions of germ cell lineage of the mouse
… Y chromosome do not have pairing partners during male meiosis. As a result they become silenced during this time. One mechanism that has been proposed to compensate for inactive X-linked housekeeping genes during male meiosis is X-to-autosome retropositions. We have identified a mutation within an …
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Functional analysis of the Argonaute family proteins during early embryonic and germ cell development in the mouse
… PIWI-proteins in the mouse leads to a block in male meiosis. Strikingly, loss of Miwi2 causes an additional progressive loss of germ cells, reminiscent of a stem cell phenotype. However, Miwi2 levels are high in fetal testis and become undetectable soon after birth. I generated a Miwi2tdTomato …