Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Male factor"”.
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Male Infertility: The Process to Seeking Treatment
Infertility has an effect on both males and females. Current literature focuses on women rather than men. The purpose of this study was to gain an understanding of the process that adult males go through from deciding to conceive to seeking treatment for male-factor infertility. A qualitative …
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Strategies to improve artificial insemination by donor
… a widely accepted form of treatment for severe male factor infertility. The introduction of quarantined, cryopreserved semen and the associated reduction in cycle fecundity when compared to fresh semen necessitated the development of strategies to improve the performance of frozen sperm. A …
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Giving a voice to diverse men's experiences of infertility
… based upon whether they were diagnosed with male-factor infertility, or female-factor or unknown infertility. Men with male-factor infertility were found to experience a response to diagnosis and treatment which included more avoidance and distancing behaviors in response to distress and …
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Andrological Methods of Predicting the Pregnancy Outcome of an <i>in vitro</i> Fertilization Program
… to treat several types of infertility, including male factor and idiopathic infertility. However, IVF is time consuming, costly, unpredictable, and often yields a low pregnancy rate. Thus, it would be valuable to devise laboratory procedures for better prediction of IVF outcome.</p> <p>The male …
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Compounds Modulating Calcium and Motility in Human Spermatozoa
… problem, with ART cycles increasing every year. Male factor infertility is the single most common cause of infertility in couples, and as there are no therapeutic targets for males, the only treatment option is ART, which is expensive and invasive with no guarantee of success. The development of …
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Novel Modulators of Human Sperm Motility
Male factor is the underlying cause in 50% cases of infertility, and is most commonly characterised by asthenozoospermia (reduced sperm motility). Incredibly, there is currently no known treatment for this condition, and the only option is Artificial Reproduction Technology (ART) which is expensive …
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Living with infertility: an exploratory study of men’s experience
… infertility realm is mostly dominated by the female experience and on gender differences. Despite the fact that half of the infertility issues are associated with men, research on the male experience remains limited. There has recently been a change since more studies have been carried out, but …
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Investigating the effect of phosphodiesterase inhibitors on human sperm motility and function
… apparent that the main cause of infertility is male factor. Today, ICSI represents most treatment which itself demonstrates the severity of male infertility. This may include problems with sperm concentration, motility and/or morphology. Sperm motility defects are associated with most cases of …
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IMMUNOLOGICAL CHARACTERIZATION OF SEVERE INFERTILE MEN REVEALED ALTERATIONS OF THE LYMPHOID AND MYELOID COMPARTMENTS
… worldwide up to 15% of couples; overall, a male infertility factor has been found in at least 40% of infertile couples. Several studies have shown that infertile men have a higher incidence and prevalence of cancer, chronic non-malignant morbidities, endocrinological and autoimmune …
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Protein Phosphatase 4 in human spermatozoa: investigations into location, regulatory subunits and role in motility
… cites 50% of infertility diagnosis as being of male factor origins. Surprisingly, there is very little that can be done to tackle the problem of male infertility. The key to progression in this field will be the translation of basic scientific research into the clinical laboratory. It is widely …
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Aneuploidy and DNA fragmentation in morphologically abnormal sperm
… reproductive technique for men with severe male-factor infertility. However, ICSI requires the subjective selection of normal looking sperm, which does not preclude the transmission of genetically abnormal sperm. Correlation between abnormal sperm morphology and chromosomal abnormalities has …
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Role of second generation phosphodiesterase inhibitors on mammalian sperm mobility
… While cases of infertility could be multifactorial (affecting both male and female), 50% of cases are due to male factor infertility and this is mostly characterised by reduced sperm motility (asthenozoospermia). Assisted Reproduction Technology (ART) is the only treatment option available …
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Dynamic changes of TDP-43 in testicular and epididymal sperm
… worldwide struggles with infertility with male factor accounting for half the cases, highlighting the importance of better understanding the mechanisms regulating spermatogenesis and sperm maturation. The goal of the present study was to evaluate the dynamic changes of TDP-43 from late …
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Die Bedeutung der intrazytoplasmatischen Spermieninjektion in der Behandlung der schweren männlichen Subfertilität
… sogar Konzeptionen nach ICSI mittels epididymalen und testikulären Spermatozoen ein. Ein Einfluß der auf Seite der Frau vorliegenden fertilitätsmindernden Faktoren konnte in dieser Arbeit nicht nachgewiesen werden. Demgegenüber scheint die zunehmende Anzahl an behandelten Fällen und die damit …
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Regulation of SNARE function during sperm capacitation to promote the acrosome reaction
… According to the World Health Organization, the male factor alone accounts for over one third of total infertility. There are various causes of male infertility but defective acrosomal exocytosis is perhaps one of the biggest contributors towards male infertility. Unfortunately there is little …
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Διέγερση των ωοθηκών σε γυναίκες για εξωσωματική γονιμοποίηση και ενδοσαλπιγγική μεταφορά γαμετών
… Which stimulation protocols result in satisfactory pregnancy rates and finally which are the superior stimulation protocols for follicular development in an IVF program? In order to evaluate the efficacy of different regimes in ovulation induction we studied 512 women in 575 cycles from 1985 …