Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Malaria--Research"”.
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More money, more science? : how the malaria research community responds to funding opportunities
Agencies that fund research shape both the rate and direction of scientific progress through the resource allocation choices they make. However, our understanding of the degree to which scientists respond to shifts in that allocation is very limited. How does the scientific community reorganize …
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Proteolysis-targeting chimeras as a novel strategy for targeting epigenetic mechanisms in Plasmodium falciparum parasites
… resistance to the only remaining effective antimalarial, artemisinin, novel drugs with novel modes-of-action (MoA) are needed. Current antimalarial efforts aim to identify small-molecule inhibitors that bind to the active site of essential target proteins, thereby killing the causative organism, …
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Engineering control of eukaryotic translation with application to the malaria parasite Plasmodium falciparum
… is a fundamental component of molecular biology research. In many systems, tools exist that allow generalizable control of gene expression at the transcriptional or post-transcriptional level. Plasmodium falciparum, the protozoan parasite responsible for the majority of death and sickness due to …
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Synthesis and SAR investigation of haemozoin-inhibiting quinazolines active against Plasmodium falciparum
Malaria is a potentially fatal blood disease with most deaths caused by Plasmodium falciparum. It exists in 95 countries worldwide and puts nearly 3.2 billion people at risk of contracting the disease. Despite recent advances made in malaria eradication and control including by antimalarial drugs …
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Dissecting the genetic bases of severe malaria resistance using genome-wide and post genomewide study approaches
P. falciparum malaria remains one of the leading public health problems worldwide. The global tally of malaria in 2018 was estimated at 228 million cases and 405, 000 deaths worldwide. African countries disproportionately carry the global burden of malaria accounting for 93% and 94% of cases and …
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Corpus callosum morphology in retinopathy-positive and retinopathy-negative Malawian children diagnosed with cerebral malaria
… pediatric survivors of cerebral malaria (CM). Participants were 20 children who were admitted to the Queen Elizabeth Central Hospital in Blantyre, Malawi, and satisfied the clinical case definition of CM. There were two groups: retinopathy-positive CM (n = 16) and …