Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 105 for “"Major Depressive Disorder (MDD)"”.
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ROLE OF ATM IN THE PATHOPHYSIOLOGY OF MAJOR DEPRESSIVE DISORDER (MDD)
… symptoms, including mood disturbances. Major depressive disorder (MDD) is a debilitating neuropsychiatric disease, characterized by affective, neurovegetative and cognitive symptoms and affecting about 300 million people worldwide with severe social and economic consequences. MDD is a …
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THE RACIAL AND ETHNIC DISPARITIES IN PATHWAY TO MAJOR DEPRESSIVE DISORDER (MDD) AND ITS IMPACT ON THE RECEIPT OF MDD TREATMENT
Major Depressive Disorder (MDD) is the third leading cause of death in the US and has long-term negative impact on adolescents such as failure at school, substance abuse, and adult depression [1-4]. It affects approximately 8% of adolescents every year [5, 6]. Early identification and receipt of …
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A Retrospective Claims Analysis of the Utilization of Services by Medicaid-Enrolled Adults Seeking Treatment for Major Depressive Disorder (MDD) in Washington State
… Washington State receive adequate treatment for Major Depressive Disorder (MDD) when compared to recommended treatment guidelines. This study used publicly available claims data from September 1, 2014, through September 30, 2015 to conduct an observational retrospective cohort study where a …
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Clinical And Demographic Correlates Of Depression In Stable Heart Failure
… factors present in patients with stable HF and major depressive disorder (MDD) were explored. Participants were recruited from 5 structured HF disease management programs in the Northeastern US. Measures include the Centers for Epidemiological Studies Depression Scale (CESD), the Charlson …
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Medication Adherence in Children and Adolescents with Major Depressive Disorder
Major Depressive Disorder (MDD) is a serious psychiatric disorder in children and adolescents where antidepressant adherence remains an important issue. The present study uses electronic monitoring (Medication Event Monitoring System, APREX, Fremont, California [MEMS® caps]) to compare various …
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The role of self-efficacy and attachment style: support of dietary self-care in adults with type 2 diabetes
… which evaluates empirical papers examining major depressive disorder (MDD) within a cognitive framework. A tentative model based upon a diathesis-stress framework is postulated which may account for the high prevalence of depression in type 2 diabetes. This paper was prepared for submission …
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Aerobic Exercise and Hippocampal Plasticity in Young Adults with Depression
Major depressive disorder (MDD) is a significant public health problem. Exercise has shown promise in reducing symptoms and promoting brain plasticity in MDD. A relationship between symptom severity, hippocampus volume and N-acetyl-aspartate (NAA) concentration, a marker of neuron …
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Mental health and couple communication
… couples with one spouse/partner diagnosed with Major Depressive Disorder (MDD). The study consisted of two groups that included couples with one spouse/partner diagnosed with MDD who were recruited from an inpatient psychiatric unit and a comparison group. This research was conducted to identify …
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Clinical, Metabolic and Inflammatory Indicators of Esketamine Efficacy for Treatment-Resistant Major Depressive Episodes
Major depressive disorder (MDD) is a common and debilitating condition. When it becomes difficult to treat, it poses a significant challenge. Individuals with treatment-resistant depression (TRD) often experience severe symptoms and elevated suicide risk. Metabolic and inflammatory abnormalities …
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Translational Regulation in Excitatory Neurons Controls Stress Reactivity and the Antidepressant Response to Ketamine
Major depressive disorder (MDD) is a leading cause of disability worldwide, with nearly one-third remaining treatment-resistant. Chronic stress is a major risk factor for MDD, whereas acute stress is adaptive and mediated by hypothalamic-pituitary-adrenal axis activation. Ketamine produces rapid …
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Vocal modulation features in the prediction of major depressive disorder severity
… biomarkers of neurological disease, particularly Major Depressive Disorder (MDD). Two model components contribute to amplitude modulation (AM): AM from respiratory muscles and from interaction between formants and frequency modulation in the fundamental frequency harmonics. Based on the modulation …
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Analysis of affective instability on ecological momentary assessments data: successive difference, variance decomposition, and mean comparison via multilevel modeling
… a defining characteristic of some psychological disorders such as Borderline Personality Disorder and mood cycling disorders. Use of Ecological Momentary Assessments (EMA) enables researchers to directly assess such frequent and extreme fluctuations over time. Two specific operationalizations of …
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Obesity and outcomes of bariatric surgery: A focus on patients with postoperative substance use disorders
… an increased risk for developing substance use disorders (SUDs) has brought to light the importance of understanding how the postoperative development of a SUD may affect weight loss and psychosocial outcomes. The present investigation used a quasi- experimental, non- equivalent, matched pair …
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Association between Reward Sensitivity and Smoking Status in Major Depressive Disorder
… not differ between individuals with and without major depressive disorder (MDD). In addition, a negative correlation between reward sensitivity and striatal prediction error signal was found among smokers, consistent with the suggestion that enhanced tonic dopamine associated with increased …
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The Temperament - Psychopathology Link: How Does Difficult Temperament Predict Risk for and Presentation of Major Depression Among Offspring at High and Low Risk for Depression
… difficult temperament predicts offspring major depression, while adjusting for family effect. Second, we sought to examine the pathoplasty model of the relationship between temperament and psychopathology by examining how offspring difficult temperament affects qualitative features of …
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An Examination of Affective Blunting in Rodents
<p>Major Depressive Disorder (MDD) is the leading cause of disability worldwide. The prevalence of MDD is 12% in men and 20% in women. Antidepressant drugs are the first line of treatment in Major Depressive Disorder and other mood disorders, particularly selective-serotonin reuptake inhibitors. …
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Depression and PTSD as Predictors of Dementia and Other Cognitive Disorders among Veterans based on Race and Sex
In the literature, depression (especially major depressive disorder [MDD]) and posttraumatic disorder (PTSD) have been known to significantly increase individuals’ risk for dementia. Dementia affects 5 to 7 percent of the population across the world. Compared to the general U.S. population, the …
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Translational Neuroimaging of Emotion Processes in Posttraumatic Stress Disorder and Depression
… are central features of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD), which are linked to altered neural response patterns. However, inconsistent results have led to questions about the reliability of such findings. Heterogeneous clinical presentations across …
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Change in Psychosocial Functioning During Cognitive Therapy for Depression
Major Depressive Disorder (MDD) is a highly prevalent and recurrent disorder that impairs peoples' work, relationships, and leisure activities. Cognitive Therapy (CT) improves this impairment in psychosocial functioning in adults with MDD, but questions remain as to how improvements occur both …
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Anxiety and Anhedonia in Major Depressive Disorder: The Contributing Roles of Neuroticism, Cognitive Control, and Reward Learning
… of anxiety and higher levels of anhedonia in Major Depressive Disorder (MDD) are two clinical presentations linked to poorer depression treatment outcomes. However, the mechanisms contributing to these symptom presentations remain unclear. Neuroticism, impaired cognitive control, and blunted …
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