Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Magnetic resonance imaging (MRI) contrast agents"”.
-
Gadolinium Endohedral Metallofullerenes for Future Magnetic Resonance Imaging Contrast Agents
… shown the potential to become next generation magnetic resonance imaging (MRI) contrast agents due to their significantly improved efficiency and safety, as well as multi-day body retention which allows for a longer surgery and observation compared to current contrast agents. In Chapter 1, I …
-
Dinitroxides in Rapid Scan Electron Paramagnetic Resonance Imaging
… disease behavior. Rapid Scan (RS) electron paramagnetic resonance (EPR) offers a unique, non-invasive tool for investigation of these so-called microenvironments through EPR Imaging (EPRI). Research into advancement of EPRI falls into many categories. Not least among those are advances in …
-
Chemical and Biological Strategies for Improving the Sensitivity of SPIO-Enhanced MR Imaging
… favorable. The field of cellular and molecular imaging has emerged as a cutting-edge technology that provides a biological toolkit capable of assessing cellular and genetic deviations at their earliest stages, offering a promising new avenue for early stage cancer diagnosis. In particular, the …
-
The Design and Study of Lanthanide-Chelating Macromolecular Diagnostic and Delivery Agents
Macromolecular magnetic resonance imaging (MRI) contrast agents have unique localization and contrast enhancement properties. We have designed and studied a monodisperse paramagnetic β-cyclodextrin click cluster (Gd10) decorated with Gd-containing arms and unique contrast enhancing polymers. To …
-
Synthesis and Functionalizations of Trimetallic Nitride Template Endohedral Metallofullerenes (TNT-EMFs)
… potential for medical applications, such as magnetic resonance imaging (MRI) contrast agents, X-ray contrast agents and nuclear medicine. The TNT-EMFs have inherent advantages over other endohedral metallofullerenes, such as M@C60 and M@C82, due to the encapsulation of up to three metal atoms …
-
The Preparation, Functionalization and Biomedical Applications of Carbonaceous Nanomaterials
… weight of the PEG from 350 to 5000. The 1H magnetic resonance relaxivities of the materials were studied at 0.35 T, 2.4 T and 9.4 T. Their relaxivities were found to increase as the molecular weight of the PEG decreased, which is attributed to the increasing aggregate size. The aggregate …
-
Fullerene Based Nanomaterials for Biomedical Applications
… a potential new nanoplatform for next-generation magnetic resonance imaging (MRI) contrast agents, given their inherent higher 1H relaxivity than most commercial contrast agents. The fullerene cage is an extraordinarily stable species which makes it extremely unlikely to break and release the …
-
Fluorinated Graphene Oxide: structure, morphology and its potential use in biological applications
… for the first time as a potential multimodal contrast agent, drug carrier as well as a photothermal therapy. FGO is a sheet like material with oxygen and fluorine functional groups present in the structure, a complete characterization of the material is offered in the following pages. …