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Showing 1 to 8 of 8 for “"Magnetic Particle Imaging (MPI)"”.
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Detection and Quantification of Cells using Magnetic Particle Imaging and Magnetic Microspheres
Magnetic particle imaging (MPI) is an emerging imaging modality that specifically detects superparamagnetic iron oxide nanoparticles (SPIOs). Our lab has shown that cell tracking with magnetic resonance imaging (MRI) has very high sensitivity, but low specificity and quantification of iron labeled …
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Design and Fabrication of High Frequency Electromagnetic Coil for Magnetic Particle Imaging
Magnetic Particle Imaging (MPI) is a promising modality which uses Magnetic Nanoparticles (MNPs) for tracer-based imaging in biomedical applications. Aside from their use in imaging, MNPs are increasingly being utilized for therapeutics, controlled targeted drug delivery, and diagnostics. These …
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Design, Construction, and Validation of Magnetic Particle Imaging Systems for Rodent, Primate, and Human Functional Neuroimaging
Non-invasive neuroimaging techniques, such as functional magnetic resonance imaging, enabled a paradigm shift in the way neuroscientists study the brain. With these techniques, different levels of brain function can be safely localized in humans, allowing the study of diseases. However, due to the …
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Magnetic particle imaging for intraoperative breast cancer margin assessment and functional brain imaging
Magnetic Particle Imaging (MPI) is an emerging tracer-based imaging modality that uniquely images the nonlinear magnetization of superparamagnetic iron oxide nanoparticles (SPIOs). MPI boasts high sensitivity, zero background signal, positive contrast, fast temporal resolution, and quantitative …
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Surface Modifications of Iron Oxide Nanoparticles for Magnetic Imaging and Diagnosis
Contrast agents are commonly used in magnetic resonance imaging (MRI) for their ability to selectively highlight or darken image brightness from different tissue components depending on their chemical nature. This work explores and discusses potential of colloidal iron oxide nanoparticles as …
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In vivo multi-modal imaging approaches for cancer, stem and immune cells
Introduction: Molecular imaging allows for non-invasive longitudinal visualization of cellular functions in vivo. This area of research has provided better understanding of fundamental molecular and biochemical processes, enabled optimization of pre-clinical and clinical assessments for new …
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Single-sided magnetic nanoparticles imaging scanner for early detection of breast cancer
Electromagnetic coils form the basis of magnetic particle imaging (MPI) scanners. Previous scanner designs employ Helmholtz coil arrangement which has low sensitivity and high cost of fabrication. Furthermore, the scanners have long signal acquisition time and high memory requirement. This research …
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New approaches to diagnostic imaging: Magnetic particle imaging for human functional neuroimaging and short mid-field MRI magnet design
Part I: Magnetic Particle Imaging for Human Functional Neuroimaging While Magnetic Resonance Imaging (MRI) has revolutionized diagnostic imaging since its clinical introduction in the 1980s — primarily focusing on hydrogen nuclei — it remains fundamentally limited by the weak nature of nuclear spin …