Global ETD Search
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Showing 1 to 4 of 4 for “"MafB"”.
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Maf and Mitf transcription factors regulate pancreatic endocrine cell differentiation and function
… factors. Two of these factors, MafA and MafB, have been shown to play a major role in the regulation of several genes critical to pancreas development and endocrine cell formation. MafB is essential for both α- and β-cell differentiation, as mice lacking MafB have fewer insulin+ and …
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The effects of diet varying in fat content on the pathogenesis of diabetes mellitus in wistar rat offspring
… and transcription factors including Pdx1, MafB, IR?, insulin and glucagon. Other pancreata were immunostained followed by image analysis of these factors. Results: In 40F neonates, Ins1, Ins2, glucagon, MafB and IRS2 mRNA expression was reduced. Further, in 30F neonates, Ins1, Pdx1 and MafB …
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Role of PARK2Gene in Maintenance of Pancreatic Beta Cell Functions
… The mRNA levels of the genes Pdx1, Mafa, Mafb, Nkx2-2, Nkx6-1, Pax4, and Irs1 that encode the pancreatic transcription factors were significantly decreased in the Park2-depleted INS-1 β-cells. In addition, the INS-1 β-cells lacking parkin exhibited decreased intracellular ATP level and …
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Specific connectivity and molecular diversity of mouse rubrospinal neurons
… red nucleus. The transcription factors tshz3 and mafB are expressed in the caudal cervical domain, whereas the chemokine fam19a4 is restricted to the caudal lumbar domain. KitL is an axon guidance molecule that is expressed in both the rostral population and the caudal cervical population. …