Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Macrolide antibiotics"”.
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DISCOVERY OF NOVEL MACROLIDE ANTIBIOTICS AND METHODOLOGY DEVELOPMENT OF N-SULFINYL METALLODIENAMINES
… consists of two components: discovery of novel macrolide antibiotics and methodology development of N-sulfinyl metallodienamines. To tackle bacterial resistance, new antibiotics are desperately needed. My research objective is to address this need by designing, synthesizing, and evaluating novel …
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Non-Antibiotic Effects of Macrolide Antibiotics of the Oleandomycin-Erythromycin Group With Special Reference to Their "Steroid-sparing" Effects
… the effectiveness of triacetyloleandomycin, a macrolide antibiotic, in the treatment of bronchial asthma. The beneficial effects were attributed to the antimicrobial characteristics of this compound. However, the antiasthmatic activity of the drug was found by Towniey et al. 14-18 to be …
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Epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) in a university medical center day care facility
… Univariate analysis identified macrolide antibiotics (p=0.004), asthma medications (p=0.036), other medications (p=0.036), and previous surgery (p=0.022) as risk factors. On multivariable analysis, receipt of macrolide antibiotics (p=0.002; OR 39.6; 95% CI 3.4-651.4), and receipt …
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Expression, Reinigung und Charakterisierung von Makrolid-Glykosyltransferasen für die Synthese neuartiger Makrolid-Antibiotika
The macrolide glycosyltransferases EryCIII, EryBV, OleG2 and TylMII were produced by medium-scale fermentation of recombinant Saccharopolyspora erythraea strains. The soluble expression of all glycosyltransferase genes was verified by immunoblotting and ELISA against the C-terminal …
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Formulation and efficacy of liposome-encapsulated azithromycin for pulmonary infection due to Pseudomonias Aeruginosa
… strains and potential side effects of antibiotics usage. Liposomal encapsulation of macrolide antibiotics such as azithromycin show increased drug concentrations at the site of infection, along with reduced toxic effects. In this thesis work, liposome-loaded azithromycin formulation was …
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Activating Aldehyde C-H Bonds: Applications to Hydroacylation and Transfer Hydroformylation
… to complex bioactive molecules, including macrolide antibiotics, indole alkaloids, steroids, and terpenes. Mechanistic studies revealed that a benzoate counterion acts a proton shuttle to enable transfer hydroformylation.
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The determination of veterinary antibiotics in live animals and animal products
… foods of animal origin. The aminoglycosides and macrolides are two families of antibiotics that are very similar in structure and have important applications in veterinary medicine. These antibiotics are widely used in the treatment of bacterial infections e.g. aminoglycosides for enteritis and …
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TOWARD A BETTER CLEANING AND SELECTIVITY IN ELECTROANALYSIS: TIO2-BASED SENSORS AND ENANTIOSELECTIVE MATERIALS
… set. These substances include pharmaceuticals (macrolide antibiotics, estrogenic hormones, carbamazepine, diclofenac, ibuprofen), industrial chemicals (bisphenol A), metals (silver) and pesticides (triclosan, nicosulfuron, glyphosate, neonicotinoids, pyrethroids). Modern analytical techniques …
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Molecular Characterization of Fluoroquinolone Resistance in Streptococcus pneumoniae
… strains with resistance to the ß-lactam and macrolide antibiotics has complicated the treatment of pneumococcal infections and created a need for new agents. Recently developed compounds within the fluoroquinolone group of antimicrobials have shown potential as anti-pneumococcal antibiotics. …