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Showing 1 to 2 of 2 for “"Macrocyclic Polyamines"”.
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Macrocyclic Polyamines and Their Metal Complexes Targeting HIV-1
M40401 is a well known antioxidant and as of late, it has been studied for anti- HIV properties. It was reported to reduce apoptosis of astrocytes caused by HIV- 1 infected macrophages (M/M) supernatants, and in 2005, a poster presented at the International Conference for Antiviral Research claimed …
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Synthesis of Macrocyclic Polyamines and their Cu, Fe, Mn and Zn Complexes Targeting HIV (AIDS).
Macrocyclic polyamines cyclotriazadisulfonamide (CADA) and bicyclam AMD3100 act as entry inhibitors against HIV by different mechanisms. The manganese complex of pyridine-fused macrocyclic polyamine (M40401) has been found to reduce HIV-1 induced apoptosis of astroglial cells. Based on these …