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Showing 1 to 1 of 1 for “"MYLS22"”.

  1. The Mitochondrial Fusion Protein, Optic Atrophy 1 (OPA1), Alters Cellular Metabolism to Support Cancer Cell Viability

    … could be triggered using a novel OPA1 inhibitor, MYLS22. At the transcript level, MYLS22 treatment led to changes that largely overlapped with gene silencing data. In sum, we demonstrate that targeting of OPA1 and mitochondrial fusion leads to metabolic reprogramming events correlated to decreased …

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