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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 86 for “"MYB"”.
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Análisis funcional de genes reguladores R2R3-MYB de "Arabidopsis Thaliana"
… familia de reguladores de la transcripción R2R3-MYB utilizando como sistema modelo A.thaliana por su utilidad para el analisis genetico y molecular. Con este objetivo, hemos iniciado una estrategia basada en tecnicas de genetica reversa para identificar mutantes en genes de la familia R2R3-MYB, …
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Early land plant origins of the MYB-bHLH-WDR complex
… transcriptional complexes composed of a MYB transcription factor, a bHLH transcription factor and a WD repeat scaffold (MYB-bHLH-WDR or MBW complexes) regulate patterns of flavonoid pigments, trichomes and root hairs in this cell layer. We reasoned that investigating the origins and …
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Analyse und Visualisierung eines R2R3-MYB / bHLH Transkriptionsfaktorkomplexes aus Arabidopsis thaliana
… transcription factors were analysed in detail, MYB75 as well as BHLH2/BHLH42 and TTG1. These are regulators of the dihydroflavonol-reductase (DFR), the key enzyme of the anthocyanin biosynthesis. To understand the regulatory mechanism, binding of transcription factors among each other and to the …
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Characterization of a plant-specific membrane-tethered myb transcription factor in Arabidopsis thaliana
… et al. 2006, a protein was identified as being a MYB transcription factor that was associated with the endoplasmic reticulum (ER) and was subsequently postulated to be a putative MTTF. This previously uncharacterized membrane-anchored MYB (maMYB) has two transmembrane domains and an R2R3-MYB …
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Role of subfunctionalized MYB paralogs in the evolution of pigmentation patterning in Clarkia
… pigments, always involves subfunctionalized MYB paralogs that each control the initiation of pigmentation in a specific pattern element. These early studies have mostly focused on the mechanism for patterning, though, and few have looked at the evolution and diversification of this complex …
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Distinguishing the Role of the c-myb Proto-Oncogene in Mouse Models of Cardiovascular Disease
… the specific roles of transcription factor c-myb in leukocytes, comparatively little is known about c-myb in the context of cardiovascular disease. c-myb regulates vascular smooth muscle cell (VSMC) differentiation from embryonic stem cells, as well as the proliferation of mature VSMCs. The …
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Characterisation of two genetic loci involved in fetal haemoglobin production: BCLIIA and HBSIL-MYB intergenic region
… on chromosome 6 between the genes HBS1L and MYB, known as HMIP. Histone modification and RNA polymerase II binding at these loci and at the globin genes themselves were analysed using microarray-based chromatin immunoprecipitation studies of primary human erythroid progenitor cells. In …
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Estudio de genes de la familia MYB relacionados con la tolerancia al estrés salino en Lotus spp
Fil: Lusetti, Luisina. Universidad Católica Argentina. Facultad de Ingeniería y Ciencias Agrarias; Argentina
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Evolution and Genetics of Floral Color Polymorphisms in Clarkia gracilis ssp. sonomensis and Erythronium umbilicatum
… the cup pigmentation is controlled by an R2R3-MYB transcription factor using transcriptome analysis, gene expression assays and cosegregation examination. I also found that petal pigmentation requires at least four R2R3-MYB genes, each gene exhibiting a spatiotemporal expression pattern that is …
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Identificazione e analisi funzionale di fattori regolatori dei geni globinici
… of F cell and β-thalassemia severity: the HBS1L-MYB intergenic region and the BCL11A gene. In order to understand the functional role of the associated variants at these loci we applied “Genome Wide Chromosome Conformation Capture” (Hi-C), followed by a novel technique for a selective enrichment …
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Investigating Adult Stem Cell Lineage Specification in the Freshwater Flatworm Schmidtea mediterranea
… a MEX3 homolog (Smed-mex3-1) and a putative MYB-type transcription factor (Smed-myb-1) as regulators of ASC differentiation. This body of work demonstrates that (A) mex3-1 is a critical factor broadly required for ASC differentiation, and (B) myb-1 is a regulator of the early temporal window …
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Studies on the genetic basis for thermotolerance in Arabidopsis thaliana
… a construct designed to constitutively express a MYB transcription factor were characterized. This MYB has been shown to confer salinity tolerance in Arabidopsis, and transcript profiling using cDNA microarrays had identified several sequences may be under the control of this MYB. Quantitative PCR …
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Untersuchungen zu Regulatoren der Flavonoidbiosynthese in Arabidopsis thaliana : eine Studie zu neuen Funktionen bekannter Proteinklassen
… areas of the seed. The PFG genes encode the R2R3-MYB transcription factors MYB11, MYB12 and MYB111, which are flavonol specific regulators. They are known to activate some genes, which are encoding enzymes of the flavonoid metabolism, like for example CHS and FLS. There were hints for further …
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Funktionelle Charakterisierung der humanen Polo-Kinase Plk2/Snk im Zell- und Centrosomenzyklus
… Hilfe des Zwei-Hybrid-Screens in Hefe konnte c-Myb, ein Transkriptionsfaktor der hauptsächlich in hämatopoietischen Zellen exprimiert wird, als Substrat für Plk2 am G1/S-Übergang identifiziert werden. Da die Plk2-Kinase ebenfalls in hämatopoietischen Zellen exprimiert wird, könnte sie die …
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Caracterización de MYBBP como un nuevo gen supresor de tumores
… de glucosa en el que identificamos el gen MYB binding protein 1A (MYBBP1A). MYBBP1A es un regulador de factores de transcripción implicado en la regulación de varios procesos biológicos esenciales. En este trabajo hemos analizado muestras de tumores humanos, confirmando que la pérdida de …
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MicroRNAs and Trans-acting siRNA pathways in Apple (Malus x domestica Borkh.) and Peach (Prunus persica)
… and miR858 can collectively target up to 81 MYB genes potentially involved in diverse aspects of plant growth and development. In contrast to the location of the miR159 target site in a sequence-divergent region, the target sites of miR828 and miR858 are located in the region encoding the …
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Characterization of DNA Binding Activities at Vertebrate Telomeres
… factors, TRF1 and TRF2, which both contain one Myb-type repeat. We have conducted a detailed analysis of the DNA binding mode of TRF1 and shown that it binds DNA as a dimer by contacting a bipartite DNA site with each Myb domain. The relative orientation and spacing of the two sites does not …
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