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Showing 1 to 4 of 4 for “"MVB sorting"”.

  1. Regulation of The Escrt Function of Alix

    <p>The ESCRT (endosomal sorting complex required for transport) is an evolutionary conserved membrane remodeling machinery that performs membrane invagination and abscission. ALIX is a widely expressed adaptor protein that is critically involved in three classical ESCRT-mediated processes, …

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  2. The Ubiquitin Ligase Ube4B Is Required For Efficient Epidermal Growth Factor Receptor Degradation

    … late endosomes/multivesicular bodies (MVBs), before being degraded in the lysosome. The MVB is a subset of late endosomes characterized by the appearance of small vesicles in its luminal compartment. These vesicles contain cargo proteins sorted from the limiting membrane of the MVB. …

    uthsc Repository record for The Ubiquitin Ligase Ube4B Is Required For Efficient Epidermal Growth Factor Receptor Degradation (opens in a new tab)

  3. Molecular Analysis of the Unconventional Export Machinery of HASPB, a component of the surface coat of Leishmania parasites

    … be exported via vesicles being released by the MVB sorting machinery. Furthermore employing linear sucrose gradients and electron microscopy, these vesicles corresponded to the reported density of 1.15 g/ml for exosomes (Heijnen et al., 1999) as well as to the exosomal size with diameters <100 …

    heid-diss Repository record for Molecular Analysis of the Unconventional Export Machinery of HASPB, a component of the surface coat of Leishmania parasites (opens in a new tab)

  4. The mode of action of Epicoccum derived antimicrobials

    … protein endocytosis and multivesicular body (MVB) sorting pathways, and β-oxidation of fatty acids. To our knowledge, this was the first time to report a polyene class of antifungal compound directly affecting sphingolipids – possibly not ergosterol, which is a well-known target of other drugs …

    auckland-ms Repository record for The mode of action of Epicoccum derived antimicrobials (opens in a new tab)