Global ETD Search
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Showing 1 to 6 of 6 for “"MUC4"”.
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Pancreatic Cancer - Early Detection, Prognostic Factors, and Treatment
… have reported that mucins, especially the MUC4 mucin, may confer resistance to the chemotherapeutic agent gemcitabine and may serve as targets for the development of novel types of intervention. Aim: The aim of the thesis was to investigate strategies to improve management of pancreatic …
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Separation and purification of mucins and tenascin-C in breast milk of patients and the investigation of the role of mucins and tenascin-C in the inhibition of HIV-1
… Previously in our laboratory, MUC1 and MUC4 has been implicated in the inhibition of HIV-1 in an in vitro assay. Furthermore, crude breast milk was tested in this assay showing strong HIV-1 neutralisation. Pasteurisation (80°C for 10 minutes) of both HIV positive and negative breast milk …
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Mucin expression in normal and diseased states of the stomach : a histochemical and immunohistochemical study
… Normal controls were immunoreactive for MUC4, 5 and 6, and gastritis specimens showed similar results, although the latter showed more MUCJ immunoreactivity. Whereas early foetal stomach showed no MUC immunoreactivity, MUC4, 5 and 6 were present from the early second trimester onwards. …
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Characterization of Ocular Surface Pathology and Tear Film Dysfunction Due to Type 1 and Type 2 Diabetes Mellitus
… distribution of membrane-tethered mucins (MUC1, MUC4 and MUC16), their o-glycosylated side chains and glycosyltransferases. However, high glucose reduced the gene expression of several key protein mediators involved in the cell cycle and proliferation of ocular surface epithelial cells, …
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Pathogenesis of Dry Eye in Graft Versus Host Disease (GVHD): Role of Ocular Mucins and Conjunctival Fibrosis
… glycocalyx, a decrease in ocular surface mucins, MUC4 and MUC5AC and loss of conjunctival goblet cells. Our data showed that topical treatment by mucin secretagogue, rebamipide, partially attenuates GVHD-associated damage to ocular surface. Hyperosmolar tears are a consistent feature of dry eye …
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An evaluation of genetic markers for forensic identification of human body fluids
… and UCE (reference genes), CRYP2B7P1, SFTA2, MUC4 and L. crispatus (vaginal secretion). Extensive validation, which include sensitivity, specificity, reduced volume reactions, degradation, reproducibility, mixtures, cycle number and mastermix, was carried out in accordance with the guidelines …