Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"MUC13"”.
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MUC13 Enhances Colorectal Cancer Metastasis
… of the key steps in metastasis.</p> <p>The mucin MUC13 when aberrantly overexpressed in cancer has been found to lead to poor outcomes in Pancreatic, Ovarian, Liver, and Colorectal cancer. When overexpressed in these cancers MUC13 has been shown to increase the oncogenic activity and survival of …
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MUC13 Modulated Nanomechanical and Biophysical Responses in Pancreatic Cancer Cells
… that the altered expression of mucins, including MUC13, may be useful molecular signatures for early disease diagnosis, chemotherapy response and predicting patient survival. MUC13, a recently identified transmembrane glycoprotein, is normally associated with forming a protective barrier on …
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Development of Novel Therapeutic Strategies for Pancreatic Cancer Treatment
… resistance to available therapies.</p> <p>Mucin, MUC13 is transmembrane glycoprotein, which is aberrantly overexpressed in PanCa and promoting cancer growth. Structural domains of MUC13, lead to oncogenic characteristics during cancer progression. Our lab previously established the role of MUC13 …
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Molecular Mechanisms of Metabolic Reprogramming in Pancreatic Cancer
… outcomes. Our lab has established the role of MUC13 protein in pancreatic cancer development. Another interesting molecule, Protein Kinase D1 has been reported to play essential role in hypoxic metabolism in squamous cell carcinoma, and glucose uptake in cardiac hypertrophy. Also, it has been …
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The Influence of Preovulatory Estradiol on Uterine Transcriptomics and Proteomics Around Maternal Recognition of Pregnancy in Beef Cattle
… and 179 were upregulated (PRSS8, FABP3, IDO1, MUC13, CXCL10) in the highE2/conceptus group. There were 48 differentially expressed proteins (DEPs) among the highE2/conceptus and lowE2/conceptus groups (19 upregulated, 29 downregulated in the highE2/conceptus group), 6 of these were …
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Modelling human liver bud development in vitro
… and extra-hepatic cholangiocytes (ACE2+MUC13+). By performing extensive snRNAseq analyses across HepBud formation, I was able to validate that hepatic specification in HepBuds follows a natural developmental path forming hepatoblast which strongly resemble 5/6pcw human foetal …