Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"MSLN"”.
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Development of recombinant immunotoxins targeting overexpressed cell surface biomarkers trophoblast cell-surface antigen 2 and mesothelin for cervical cancer treatment
… cell surface antigen 2 (TROP2) and mesothelin (MSLN), which are overexpressed in cervical cancer cells. Targeting TROP2 and MSLN presents a promising therapeutic approach. The study aimed to develop novel recombinant anti-TROP2 and anti-MSLN immunotoxin candidates based on truncated Pseudomonas …
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Impact of early nutrition on the development of lung immunity in the piglet
… were collected. Immune cells in the lungs, MSLN and TLN were analyzed through a variety of techniques. T lymphocyte subpopulations were identified using flow cytometry, cytokine mRNA expression was evaluated via RT-PCR, and total IgG, IgM, and IgA concentrations in serum were analyzed using …
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Development of potential immunodiagnostic & therapeutic techniques using SNAP-fusion proteins as tools for the validation of Triple-negative Breast Cancer
… (which is overexpressed in 13-76% of TNBCs), and MSLN (which is overexpressed in 67% of TNBCs) as potential targets for monospecific therapy. The evolution of antibody-based immunotherapy strategies has led to applications of single chain variable fragment (scFv) & single domain/nanobody (VHH) …
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Advancing Ovarian Cancer Diagnostics: Discovering Potential Protein Biomarkers in Extracellular Vesicles
… candidate biomarkers: APEH, CPNE3, FARSA, MSLN and PSMB9. However, subsequent ELISA showed that the exo-protein concentrations of these four candidates did not differ significantly in a small case-control study. As a result, this led us to our second study to explore alternative sources of …