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Showing 1 to 4 of 4 for “"MSL proteins"”.

  1. The Mechanism Of Regulation Of Autosomal Heterochromatic Genes In drosophila Melanogaster Males By rox Rna And Msl Proteins

    … by the ribonucleoprotein Male Specific Lethal (MSL) complex that binds hundreds of sites along the X chromosome and modifies chromatin to facilitate transcription. Loss of <i>roX</i> RNA, an essential component of the MSL complex, reduces expression from X-linked genes. Surprisingly, loss of …

    wayne-thes Repository record for The Mechanism Of Regulation Of Autosomal Heterochromatic Genes In drosophila Melanogaster Males By rox Rna And Msl Proteins (opens in a new tab)

  2. Rox1 function in dosage compensation: structural / functional analysis of a non-coding rna

    … X chromosome monosomy. The male-specific lethal (MSL) complex, containing five proteins, localizes to the male X chromosome and alters chromatin to modify gene expression. roX1 and roX2 RNAs are redundant components of MSL complex that are required for its exclusive X-localization. Recent studies …

    wayne-thes Repository record for Rox1 function in dosage compensation: structural / functional analysis of a non-coding rna (opens in a new tab)

  3. Investigation Of X Chromosome Recognition: The Role Of Small Rna In Drosophila Dosage Compensation

    … This is achieved by the Male Specific Lethal (MSL) complex, which consists of two large, non-coding RNA on the X transcripts (<i>roX1</i> and <i>roX2</i>) and five proteins. The roX RNAs have a critical role in complex localization to the X chromosome. Simultaneous mutation of <i>roX1</i> and …

    wayne-thes Repository record for Investigation Of X Chromosome Recognition: The Role Of Small Rna In Drosophila Dosage Compensation (opens in a new tab)

  4. Sex And Heterochromatin: An Investigation Of Sexual Dimorphism In Drosophila Melanogaster

    … roX RNA and some of the Male Specific Lethal (MSL) proteins, all components of the dosage compensation complex, are required for full expression of autosomal heterochromatic genes in male flies but not in females. This was surprising since heterochromatin is generally not thought to be sexually …

    wayne-thes Repository record for Sex And Heterochromatin: An Investigation Of Sexual Dimorphism In Drosophila Melanogaster (opens in a new tab)